Juvenile Idiopathic Nonspecific Interstitial Pneumonia. and Review of Literature

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概要

• 論文の詳細を見る

• We describe a case of juvenile idiopathic nonspecific interstitial pneumonia (NSIP). This is the first report of a Japanese patient with idiopathic NSIP aged 27 years. A computed tomographic scan of the chest showed groundglass opacities and reticular opacities in subpleural distribution. Bronchoalveolar lavage fluid revealed no specific finding except for decreased CD4/CD8 ratio of lymphocyte subset. Histopathological features on examination of thoracoscopic lung biopsy specimens were consistent with those of NSIP group III. The patient was treated with corticosteroids and immunosuppressants, but no clinical improvement was noted and the general condition has gradually worsened. Although the prognosis is generally considered to be good in patients with NSIP, some patients die as a result of progression of the disease. The prediction of prognosis based on histopathological, radiologic, and bronchoalveolar lavage cell findings in NSIP seems to be difficult at present.

• 長崎大学の論文

著者

• Ida Hiroaki

  長崎大学 医学部第2内科

• Mukae Hiroshi

  Dep. Of Respiratory Disease School Of Medicine Univ. Of Occupational And Environmental Health

• Sugahara Yazuyuki

  長崎大学 医歯薬学総合研究科臨床検査医学講座

• KADOTA Jun-ichi

  Second Department of Internal Medicine, Nagasaki University

• Kadota Jun-ichi

  長崎大学 医歯薬学総合研究科第二内科学

• Kadota J

  Second Department Of Internal Medicine Oita University Faculty Of Medicine

• Hara Shintaro

  長崎大学 医学部第二内科

• Sakanaka Koji

  参天製薬奈良研究開発センター

• Kadota Jun-ichi

  Second Department Of Internal Medicine Faculty Of Medicine Oita University

• KAKUGAWA Tomoyuki

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• NAGATA Towako

  the Second Department of Internal Medicine, Nagasaki University School of Medicine

• Isii Hiroshi

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Kadota Jun-ichi

  The Second Department Of Internal Medicine Ngasaki University School Of Medicine

• Ishii Hiroshi

  長崎大学 医学部第二内科学

• Nagata Towako

  The Second Department Of Internal Medicine Nagasaki University School Of Medicine

• Kaida Hideyuki

  The Second Department Of Internal Medicine Nagasaki University School Of Medicine

• Kakugawa Tomoyuki

  Second Department Of Internal Medicine Nagasaki University School Of Medicine

• Ishii Hiroshi

  Department Of Internal Medicine Isahaya Insurance General Hospital

• Ishii Hiroshi

  Second Department of Internal Medicine, Nagasaki University School of Medicine

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