Respiratory Bronchiolitis-associated Interstitial Lung Disease with Unusual Histopathological Findings
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概要
- 論文の詳細を見る
Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a mild inflammatory reaction commonly seen in asymptomatic young male cigarette smokers. This report describes unusual pathological findings in a 63-yearold Japanese female with RB-ILD. She had a 40 pack-year smoking history. Chest computed tomography showed multiple patchy shadows, especially in the right lower lobe. Diagnosis could not be established by bronchoalveolar lavage and transbronchial lung biopsy. Thoracoscopic lung biopsy was performed from right S5 and S9, which demonstrated the typical pathological findings of RB-ILD, including the presence of pigmented macrophages within respiratory bronchioles, thickening of alveolar septa by fibrosis, accumulation of intrapulmonary blue bodies and lack of granulomatous changes. Our patient had atypical RB-ILD based on old age at presentation (commonly -40 years of age), marked fibrosis and presence of numerous blue bodies.
- 長崎大学の論文
著者
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Kohno Shigeru
長崎大学 医学部第二内科
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Sugahara Kazuyuki
長崎大学 医歯薬学総合研究科臨床検査医学講座
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Kawakami Shigeru
京都大学 薬学研究科
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Kawakami S
Department Of Laboratory Medicine Nagasaki University Graduate School Of Biomedical Sciences
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Sugahara Yazuyuki
長崎大学 医歯薬学総合研究科臨床検査医学講座
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Sugahara Yazuyuki
Dep. Of Lab. Medicine Nagasaki Univ. Graduate School Of Biomedical Sciences Nagasaki Univ. Hospital
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Tomari Shinya
Second Department of Internal Medicine, Nagasaki University School of Medicine
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MATSUSE Hiroto
Second Department of Internal Medicine, Nagasaki University School of Medicine
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Matsuse Hiroto
Second Department Of Pathology Nagasaki University School Of Medicine
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Matsuse Hiroto
The Second Department Of Internal Medicine Nagasaki University School Of Medicine
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Tomari Shinya
Second Department Of Internal Medicine Nagasaki University School Of Medicine
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