A case of reversible posterior leukoencephalopathy syndrome in a patient on peritoneal dialysis.
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概要
- 論文の詳細を見る
Reversible posterior leukoencephalopathy syndrome (RPLS) is a recently identified clinical and radiologic entity. The characteristic radiologic findings are bilateral gray and white matter edema in the posterior regions of the cerebral hemispheres. The typical clinical syndrome includes headache, confusion, visual symptoms, and seizures. RPLS most often occurs in the setting of hypertensive crisis, preeclampsia, or with cytotoxic immunosuppressive therapy, but many other clinical settings are described, such as cryoglobulinemia, hemolytic uremic syndrome, systemic lupus erythematosus, and use of erythropoietin. A 24-year-old man, diagnosed as having anaphylactoid purpura nephritis at 12 years of age and who started peritoneal dialysis (PD) at 23 years of age, was admitted to our hospital with a seizure and consciousness disturbance. His blood pressure (BP) and body fluid volume had not been controlled well because of poor compliance with medication and PD. T2-weighted magnetic resonance imaging (MRI) revealed high signal intensity changes restricted to the cortex and subcortical white matter of the cerebellum. On the other hand, diffusion-weighted imaging showed an isointense signal. From these findings, he was diagnosed as having RPLS. With appropriate control of BP and volume control by PD and hemodialysis, his symptoms improved, and a follow-up cranial MRI 1 month later was almost normal. To the best of our knowledge, this is the first report of RPLS in an adult PD patient.
- Springerの論文
- 2010-12-01
著者
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Kohno Shigeru
長崎大学 医学部第二内科
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Kamihira Shimeru
長崎大学 医歯薬学総合研究科臨床検査医学講座
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Sugahara Kazuyuki
長崎大学 医歯薬学総合研究科臨床検査医学講座
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Kawakami S
Santen Pharmaceutical Co. Ltd. Nara Research And Development Center:department Of Hospital Pharmacy
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Kawakami Shigeru
Dep. Of Drug Delivery Res. Graduate School Of Pharmaceutical Sciences Kyoto Univ.
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Otsu Yoshiko
長崎大学 医歯薬総研内科学第2
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Kohno Shigeru
佐世保市立総合病院 内科
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Kohno Shigeru
長崎大学医学部歯学部附属病院 薬剤部
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Kohno Shigeru
Nagasaki University
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Kawakami S
Department Of Laboratory Medicine Nagasaki University Graduate School Of Biomedical Sciences
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Sugahara Yazuyuki
長崎大学 医歯薬学総合研究科臨床検査医学講座
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Kohno Shigeru
長崎大学 第二内科
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Kohno Shigeru
東北大学加齢医学研究所 抗感染症薬開発研究部門
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Kanazawa Shigeo
公立みつぎ総合病院
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Furusu Akira
長崎大学 医学部第二内科
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Furusu Akira
Second Department Of Internal Medicine Nagasaki University Graduate School Of Biomedical Sciences
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Furusu Akira
長崎大学 医学部内科学第2
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Kawabata S
Santen Pharmaceutical Co. Ltd. Nara Research And Development Center:department Of Hospital Pharmacy
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Sakanaka Koji
参天製薬奈良研究開発センター
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OBATA Yoko
Second Department of Internal Medicine, Nagasaki University School of Medicine
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Obata Yoko
Second Department Of Internal Medicine Nagasaki University Graduate School Of Biomedical Sciences
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上平 憲
長崎大学医学部臨床検査医学
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Kanazawa Shigeo
Department Of Surgery Ishikawa General Hospital
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Kashiwagi Satsuki
School Of Pharmaceutical Sciences Nagasaki University
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Kohno Shigeru
Second Dep. Of Internal Medicine Nagasaki Univ. Graduate School Of Biomedical Sciences Nagasaki Univ
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Nishino Tomoya
Second Department Of Internal Medicine Nagasaki University
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Sakanaka Koji
Department Of Hospital Pharmacy Nagasaki University Hospital Of Medicine And Dentistry:santen Pharma
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Hirose Megumi
Second Department Of Internal Medicine Nagasaki University Of Medicine
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KITAMURA Mineaki
Second Department of Internal Medicine, Nagasaki University of Medicine
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URAMATSU Tadashi
Second Department of Internal Medicine, Nagasaki University of Medicine
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Uramatsu Tadashi
Second Department Of Internal Medicine Nagasaki University Of Medicine
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Kohno Shigeru
The Jikei University School Of Medicine
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Kitamura Mineaki
Second Department Of Internal Medicine Nagasaki University Of Medicine
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