Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
スポンサーリンク
概要
- 論文の詳細を見る
- 2008-02-10
著者
-
CHAMOTO Kenji
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
NISHIMURA Takashi
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
西村 孝司
北海道大学遺伝子病制御研究所疾患制御部門・免疫制御分野
-
Nishimura T
Division Of Immunoregulation Department Of Radiology Hokkaido University
-
Oizumi S
First Department Of Medicine Hokkaido University School Of Medicine
-
Oizumi Satoshi
北海道大学 医学部第一内科学
-
Oizumi Satoshi
First Department Of Medicine Hokkaido University School Of Medicine
-
Nishimura M
First Department Of Medicine Hokkaido University School Of Medicine
-
Yokouchi Hiroshi
First Department Of Medicine Hokkaido University School Of Medicine
-
Nishimura Masaharu
First Department of Medicine, Hokkaido University Graduate School of Medicine
-
Nishimura Masaharu
First Department Of Medicine Hokkaido University School Of Medicine
-
YAMAZAKI Koichi
First Department of Medicine, Hokkaido University, School of Medicine
-
KIKUCHI Eiki
First Department of Medicine, Hokkaido University, School of Medicine
-
SHINAGAWA Naofumi
First Department of Medicine, Hokkaido University, School of Medicine
-
HOMMURA Fumihiro
First Department of Medicine, Hokkaido University, School of Medicine
-
Nakashima M
Department Of Molecular Immunology And Clinical Immunology Medical Institute Of Bioregulation Kyushu
-
Nishimura Takashi
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Nakashima M
Kyushu Univ. Fukuoka Jpn
-
Yamazaki Koichi
First Department Of Medicine Hokkaido University School Of Medicine
-
Hommura Fumihiro
First Department Of Medicine Hokkaido University School Of Medicine
-
Chamoto K
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Chamoto Kenji
Division Of Immunoregulation Institute For Genetic Medicine Hokkaido University
-
Nishimura Masaharu
First Department Of Medicine Hokkaido University Graduate School Of Medicine
-
Nishimura Takashi
Division Of Arrhythmia And Electrophysiology Department Of Cardiovascular Medicine National Cerebral
-
Nishimura Takashi
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Nishimura Takashi
Division Of Immunoregulation Institute For Genetic Medicine Hokkaido University
-
西村 孝司
北海道大学遺伝子病制御研究所・免疫制御分野
-
Shinagawa Naofumi
First Department of Medicine, Hokkaido University School of Medicine
関連論文
- Clinical characteristics of pleomorphic carcinoma of the lung
- Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions
- CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific T_h2-cell migration into lung
- 自己免疫疾患の病因・病態解析と新たな治療法の開発に関する研究
- Comparison of the Pharmacodynamics of Biapenem in Bronchial Epithelial Lining Fluid in Healthy Volunteers Given Half-Hour and Three-Hour Intravenous Infusions
- ヘルパーT細胞サブセットによる抗腫瘍免疫の制御とその臨床研究への応用 (特集 がんワクチンの展望)
- MS11-3 Th1およびTh17依存的気道アレルギーにおける気道過敏性上昇機構の解明(気管支喘息-病態生理,第58回日本アレルギー学会秋季学術大会)
- アレルギーの増加が警鐘を鳴らす免疫バランスの破綻 : スギ花粉疎開ツアーによる症状緩和と社会啓発(特別講演1,第51回アレルギー・免疫毒性研究会,地方会・研究会記録)
- NPOイムノサポートセンターが推進するイムノリゾート構想--体内環境の改善をめさしたヘルスツーリズム (特集 のんびりを楽しむ休暇)
- EL5 Th17の発見による免疫バランス制御のあらたな展開 : アレルギー,免疫病発症における意義(教育講演,第57回日本アレルギー学会秋季学術大会)
- 癌のTh1細胞治療 (あゆみ 癌免疫制御法の進歩と展望--細胞性免疫による癌治療はどこまで可能か)
- Th1/Th2バランス解析用DNAアレイフィルターの開発
- 免疫バランス制御法による次世代型がん免疫療法の開発
- 新しい癌細胞治療 : 担癌生体の免疫抑制打破のための癌特異的Th1細胞の応用
- 免疫バランス制御における樹状細胞サブセットの重要性
- Th1細胞と樹状細胞サブセット(DC1)を用いた癌ワクチン療法 (プロフェッショナル抗原提示細胞,樹状細胞)
- アレルギー発症に重要なTh1/Th2細胞の分化誘導におけるDCサブセットの役割(抗原提示細胞とT細胞の機能的分化機構)
- Th1,Th2細胞移入疾患モデルを用いたエフェクター機構の解析 (特集 Th1/Th2バランス異常と疾患)
- OVERVIEW Th1/Th2バランス制御の破綻と免疫病 (特集 Th1/Th2バランス異常と疾患)
- アトピー性皮膚炎患者におけるT細胞免疫応答
- CIR遺伝子導入retrovirus vectorを用いたCEA特異的Tc1, Th1細胞の誘導とその自家大腸癌細胞に対するターゲティング
- 食道扁平上皮癌切除組織におけるNY-ESO-1発現の検討
- 日本人の肺癌組織における癌精巣抗原NYESO-1, MAGE-A4の発現の検討と予後との関連(第105回日本外科学会定期学術集会)
- Genetic variants in mannose receptor gene (MRC1) confer susceptibility to increased risk of sarcoidosis
- Airflow limitation and airway dimensions assessed per bronchial generation in older asthmatics
- PS-161-3 キメラ免疫受容体遺伝子導入T細胞による抗腫瘍効果の検討
- Steep dose-response relationship for stage I non-small cell lung cancer using hypo-fractionated high-dose irradiation by real-time tumor-tracking radiotherapy (RTRT)
- Expression and Diagnostic Evaluation of the Human Tumor-Associated Antigen RCAS1 in Pancreatic Cancer
- Comparative Atomic Force and Scanning Electron Microscopy for Fine Structural Images of Nerve Cells
- Fine Surface Images That Reflect Cytoskeletal Structures in Cultured Glial Cells by Atomic Force Mieroseopy
- 免疫制御の中枢としてのTh1/Th2バランス
- アトピー性皮膚炎患者におけるT細胞免疫応答
- 免疫制御の中枢としてのTh1/Th2バランス
- 気道アレルギー発症とThl,Th2細胞 (Th1/Th2バランス制御とアレルギー)
- 樹状細胞サブセットによるTh1/Th2制御 (Th1/Th2バランス制御とアレルギー)
- 樹状細胞サブセットによるTh1/Th2バランスの制御 (特集 樹状細胞--免疫応答の新たな主役)
- DC1/DC2によるTh1/Th2バランスの制御と癌治療への応用 (10月第1土曜特集 細胞免疫療法の現状) -- (樹状細胞を用いた細胞免疫療法)
- Construction of the Single-Chain Fv from 196-14 Antibody toward Ovarian Cancer-Associated Antigen CA125
- Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
- HLA class I antigen expression is associated with a favorable prognosis in early stage non-small cell lung cancer
- Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer
- Expression of RCAS1 in human gastric carcinoma : A potential mechanism of immune escape
- CD4^+ T cells in cancer stroma, not CD8^+ T cells in cancer cell nests, are associated with favorable prognosis in human non-small cell lung cancers
- Expression of Human Tumor-Associated Antigen RCAS1 in Adult T-Cell Leukemia/Lymphoma
- Expression of Apoptosis-Associated Protein RCAS1 in Macrophages of Histiocytic Necrotizing Lymphadenitis
- Airflow limitation and airway dimensions in chronic obstructive pulmonary disease.
- Chemokines in bronchiolar epithelium in the development of chronic obstructive pulmonary disease.
- Extracellular matrix metalloproteinase inducer is increased in smokers' bronchoalveolar lavage fluid.
- Th1/Th2細胞と抗腫瘍免疫--癌治療にはTh1・Th2のいずれの細胞が有効か (9月第5土曜特集 造血の再生医学と細胞療法) -- (腫瘍免疫の制御)
- 抗腫瘍免疫におけるTh1/Th2バランス--Th1主導免疫の意義 (特集 癌と免疫--基礎と臨床) -- (基礎 癌免疫の基盤的研究の進歩)
- Phase I study of amrubicin and vinorelbine in non-small cell lung cancer previously treated with platinum-based chemotherapy
- Non-responsiveness to gefitinib in a patient with lung adenocarcinoma having rare EGFR mutations S768I and V769L.
- Analysis of the response and toxicity to gefitinib of non-small cell lung cancer
- 7 Need of prompt introduction of implantable LVAS into Japanese therapeutic strategy for severe heart failure(Symposium 8 (SY-08) (M) New Strategies for Management of Severe Heart Failure with New Devices and Surgery,Special Program,The 72nd Annual Scient
- The in vivo development of human T cells from CD34^+ cells in the murine thymic environment
- AFM Observation of Three-Dimensional Fine Structural Changes in Living Neurons
- An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen
- 1α,25-Dihydroxyvitamin D3 downmodulates the functional differentiation of Th1 cytokine-conditioned bone marrow-derived dendritic cells beneficial for cytotoxic T lymphocyte generation
- STAT6-mediated signaling in Th2-dependent allergic asthma : critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation
- The critical role of type-1 innate and acquired immunity in tumor immunotherapy
- Susceptibility to oxygen desaturation during bronchoscopy in elderly patients with pulmonary fibrosis
- Atomic Force Microscopy of Living Cells
- Atomic Force Microscopy in Histology and Cytology
- Predictive value of expression of P53, Bcl-2 and lung resistance-related protein for response to chemotherapy in non-small cell lung cancers
- Relationship Between Diseased Lung Tissues on Computed Tomography and Motion of Fiducial Marker Near Lung Cancer
- Mucou Gland Adenoma of the Trachea Resected with an Endoscopic Neodymium: Yttrium Aluminum Garnet Laser
- Inductively Coupled Plasma Mass Spectrometry for the Determination of Platinum Accumulation in Human Non-Small Cell Lung Cancer Cell Lines
- "Web-like Obstruction" - A Sign of Regional Complete Remission after Concurrent Chemoradiotherapy in Small Cell Lung Cancer
- 3-Methylcholanthrene-induced transforming growth factor-β-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy
- Potential of Selected Strains of Lactic Acid Bacteria to Induce a Th1 Immune Profile
- Critical role of the Th1/Tc1 circuit for the generation of tumor-specific CTL during tumor eradication in vivo by Th1-cell therapy
- The interface between innate and acpuired immunity: glycolipid antigen presentation by CD1 d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes
- Functional heterogeneity among bone marrow-derived dendritic cells conditioned by T_h1-and T_h2-biasing cytokines for the generation of allogeneic cytotoxic T lymphocytes
- Natural Killer T Cell Ligand α-Galactosylceramide Inhibited Lymph Node Metastasis of Highly Metastatic melanoma Cells
- Endobronchial Actinomycosis Associated with a Foreign Body -Successful Short-term Treatment with Antibiotics-
- Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells
- Unexpected role of TNF-α in graft versus host reaction (GVHR) : donor-derived TNF-α suppresses GVHR via inhibition of IFN-γ-dependent donor type-1 immunity
- Differential regulation of VLA-2 expression on T_h1 and T_2 cells : a novel marker for the classification of T_h subsets
- An efficient method to prepare T cell receptor gene-transduced cytotoxic T lymphocytes type 1 applicable to tumor gene cell-therapy
- Phase II Study of Gefitinib Readministration in Patients with Advanced Non-Small Cell Lung Cancer and Previous Response to Gefitinib
- Blocking of IL-6 signaling pathway prevents CD4^+ T cell-mediated colitis in a T_h17-independent manner
- Triple-site pacing : a new supported therapy approach for bridge to recovery with a left ventricular assist system in a patient with idiopathic dilated cardiomyopathy
- Antitumor activity of chimeric immunoreceptor gene-modified Tc1 and Th1 cells against autologous carcinoembryonic antigen-expressing colon cancer cells
- AsialoGM1^+CD8^+ central memory-type T cells in unimmunized mice as novel immunomodulator of IFN-γ-dependent type 1 immunity
- Interleukin-12-responding asialoGM1^+CD8^+ central memory-type T cells as precursor cells for interferon-γ-producing killer T cells
- Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.
- A novel tumor-vaccine cell therapy using bone marrow-derived dendritic cell type 1 and antigen-specific T_h1 cells
- 腫瘍微小環境由来TGF-βによって誘導される腫瘍増殖促進免疫制御細胞群の性状とその克服によるがん免疫治療 (特集 腫瘍の免疫回避機構)
- A T_h17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-γ production in order to induce airway hyperresponsiveness
- Potential of Selected Strains of Lactic Acid Bacteria to Induce a Th1 Immune Profile
- Phase II Study of Irinotecan plus S-1 Combination for Previously Untreated Advanced Non-Small Cell Lung Cancer: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0601
- P10-28 放射線治療とTh1細胞治療との併用によるマウス肺癌治療効果の増強(ポスター総括10 : 病理2 免疫・血管新生)
- Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions : a randomised trial
- Phase I study of concurrent real-time tumor-tracking thoracic radiation therapy with paclitaxel and carboplatin in locally advanced non-small cell lung cancer
- CD8+ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection
- 実地医療と臨床試験 がん特異的免疫治療の進歩と細胞治療の問題点 (特集 進化するがん免疫療法(ワクチン療法,細胞療法,抗体療法))
- The Peptide Nucleic Acid-Locked Nucleic Acid Polymerase Chain Reaction Clamp-Based Test for Epidermal Growth Factor Receptor Mutations in Bronchoscopic Cytological Specimens of Non-Small Cell Lung Cancer
- Expression of Bim, Noxa, and Puma in non-small cell lung cancer
- Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner
- ヘルパーT細胞を軸とした癌免疫応答の制御 : 基盤研究から次世代癌ワクチン, H/K-HELPの発見まで