Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells
スポンサーリンク
概要
- 論文の詳細を見る
- 2009-05-10
著者
-
ASHINO Shigeru
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
WAKITA Daiko
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
CHAMOTO Kenji
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
KITAMURA Hidemitsu
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
NISHIMURA Takashi
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
西村 孝司
北海道大学遺伝子病制御研究所疾患制御部門・免疫制御分野
-
Nishimura T
Division Of Immunoregulation Department Of Radiology Hokkaido University
-
Ashino Shigeru
Division Of Immunoregulation Department Of Radiology Hokkaido University
-
Nishimura Takashi
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
TAKESHIMA Tsuguhide
Division of Immunoregulation, Institute for Genetic Medicine, Hokkaido University
-
TOGASHI Yuji
Division of Immunoregulation, Section of Disease Control, Institute for Genetic Medicine, Hokkaido U
-
Kitamura Hidemitsu
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Togashi Yuji
Division Of Immunoregulation Department Of Radiology Hokkaido University
-
Togashi Yuji
Central Research Laboratories Tsumura & Co.
-
Tsuji Takashi
Department Of Biological Science And Technology Faculty Of Industrial Science And Technology Tokyo U
-
Tsuji Takemasa
Division Of Radiation Oncology Department Of Radiology Hokkaido University
-
OHKURI Takayuki
Division of Immunoregulation, Department of Radiology, Hokkaido University
-
OMATSU Tokuhiko
Division of Radiation Oncology, Department of Radiology, Hokkaido University
-
SHIRATO Hiroki
Division of Radiation Oncology, Department of Radiology, Hokkaido University
-
Wakita Daiko
Division Of Royce Health Bioscience Section Of Disease Control Institute For Genetic Medicine And Ho
-
Wakita Daiko
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine Hokkaido Univ
-
Chamoto K
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Chamoto Kenji
Division Of Immunoregulation Institute For Genetic Medicine Hokkaido University
-
Yahata Takashi
Division Of Immunoregulation Department Of Radiology Hokkaido University
-
Shirato Hiroki
Division Of Radiation Oncology Department Of Radiology Hokkaido University
-
Omatsu Tokuhiko
Division Of Radiation Oncology Department Of Radiology Hokkaido University
-
Ohkuri Takayuki
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Ohkuri Takayuki
Division Of Immunoregulation Institute For Genetic Medicine Hokkaido University
-
Nishimura Takashi
Division Of Arrhythmia And Electrophysiology Department Of Cardiovascular Medicine National Cerebral
-
Nishimura Takashi
Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine And Hokkaido
-
Nishimura Takashi
Division Of Immunoregulation Institute For Genetic Medicine Hokkaido University
-
西村 孝司
北海道大学遺伝子病制御研究所・免疫制御分野
関連論文
- CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific T_h2-cell migration into lung
- 自己免疫疾患の病因・病態解析と新たな治療法の開発に関する研究
- ヘルパーT細胞サブセットによる抗腫瘍免疫の制御とその臨床研究への応用 (特集 がんワクチンの展望)
- MS11-3 Th1およびTh17依存的気道アレルギーにおける気道過敏性上昇機構の解明(気管支喘息-病態生理,第58回日本アレルギー学会秋季学術大会)
- アレルギーの増加が警鐘を鳴らす免疫バランスの破綻 : スギ花粉疎開ツアーによる症状緩和と社会啓発(特別講演1,第51回アレルギー・免疫毒性研究会,地方会・研究会記録)
- NPOイムノサポートセンターが推進するイムノリゾート構想--体内環境の改善をめさしたヘルスツーリズム (特集 のんびりを楽しむ休暇)
- EL5 Th17の発見による免疫バランス制御のあらたな展開 : アレルギー,免疫病発症における意義(教育講演,第57回日本アレルギー学会秋季学術大会)
- 癌のTh1細胞治療 (あゆみ 癌免疫制御法の進歩と展望--細胞性免疫による癌治療はどこまで可能か)
- Th1/Th2バランス解析用DNAアレイフィルターの開発
- 免疫バランス制御法による次世代型がん免疫療法の開発
- 新しい癌細胞治療 : 担癌生体の免疫抑制打破のための癌特異的Th1細胞の応用
- 免疫バランス制御における樹状細胞サブセットの重要性
- Th1細胞と樹状細胞サブセット(DC1)を用いた癌ワクチン療法 (プロフェッショナル抗原提示細胞,樹状細胞)
- アレルギー発症に重要なTh1/Th2細胞の分化誘導におけるDCサブセットの役割(抗原提示細胞とT細胞の機能的分化機構)
- Th1,Th2細胞移入疾患モデルを用いたエフェクター機構の解析 (特集 Th1/Th2バランス異常と疾患)
- OVERVIEW Th1/Th2バランス制御の破綻と免疫病 (特集 Th1/Th2バランス異常と疾患)
- アトピー性皮膚炎患者におけるT細胞免疫応答
- CIR遺伝子導入retrovirus vectorを用いたCEA特異的Tc1, Th1細胞の誘導とその自家大腸癌細胞に対するターゲティング
- 食道扁平上皮癌切除組織におけるNY-ESO-1発現の検討
- 日本人の肺癌組織における癌精巣抗原NYESO-1, MAGE-A4の発現の検討と予後との関連(第105回日本外科学会定期学術集会)
- PS-161-3 キメラ免疫受容体遺伝子導入T細胞による抗腫瘍効果の検討
- 免疫制御の中枢としてのTh1/Th2バランス
- アトピー性皮膚炎患者におけるT細胞免疫応答
- 免疫制御の中枢としてのTh1/Th2バランス
- 気道アレルギー発症とThl,Th2細胞 (Th1/Th2バランス制御とアレルギー)
- 樹状細胞サブセットによるTh1/Th2制御 (Th1/Th2バランス制御とアレルギー)
- 樹状細胞サブセットによるTh1/Th2バランスの制御 (特集 樹状細胞--免疫応答の新たな主役)
- DC1/DC2によるTh1/Th2バランスの制御と癌治療への応用 (10月第1土曜特集 細胞免疫療法の現状) -- (樹状細胞を用いた細胞免疫療法)
- Efficient retroviral transduction of human B-lymphoid and myeloid progenitors : marked inhibition of their growth by the Pax5 transgene
- Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
- Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer
- Th1/Th2細胞と抗腫瘍免疫--癌治療にはTh1・Th2のいずれの細胞が有効か (9月第5土曜特集 造血の再生医学と細胞療法) -- (腫瘍免疫の制御)
- Preoperative Serum Hyaluronic Acid Level as a Good Predictor of Posthepatectomy Complications
- 抗腫瘍免疫におけるTh1/Th2バランス--Th1主導免疫の意義 (特集 癌と免疫--基礎と臨床) -- (基礎 癌免疫の基盤的研究の進歩)
- 7 Need of prompt introduction of implantable LVAS into Japanese therapeutic strategy for severe heart failure(Symposium 8 (SY-08) (M) New Strategies for Management of Severe Heart Failure with New Devices and Surgery,Special Program,The 72nd Annual Scient
- The in vivo development of human T cells from CD34^+ cells in the murine thymic environment
- An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen
- 1α,25-Dihydroxyvitamin D3 downmodulates the functional differentiation of Th1 cytokine-conditioned bone marrow-derived dendritic cells beneficial for cytotoxic T lymphocyte generation
- STAT6-mediated signaling in Th2-dependent allergic asthma : critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation
- The critical role of type-1 innate and acquired immunity in tumor immunotherapy
- Ring Opening Alkylation of Tetrahydrofuran with Some Heterosubstituted Organolithium Reagents by the Aid of Boron Trifluoride Etherate
- 3-Methylcholanthrene-induced transforming growth factor-β-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy
- Potential of Selected Strains of Lactic Acid Bacteria to Induce a Th1 Immune Profile
- Critical role of the Th1/Tc1 circuit for the generation of tumor-specific CTL during tumor eradication in vivo by Th1-cell therapy
- The interface between innate and acpuired immunity: glycolipid antigen presentation by CD1 d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes
- Functional heterogeneity among bone marrow-derived dendritic cells conditioned by T_h1-and T_h2-biasing cytokines for the generation of allogeneic cytotoxic T lymphocytes
- Natural Killer T Cell Ligand α-Galactosylceramide Inhibited Lymph Node Metastasis of Highly Metastatic melanoma Cells
- Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells
- Unexpected role of TNF-α in graft versus host reaction (GVHR) : donor-derived TNF-α suppresses GVHR via inhibition of IFN-γ-dependent donor type-1 immunity
- Differential regulation of VLA-2 expression on T_h1 and T_2 cells : a novel marker for the classification of T_h subsets
- An efficient method to prepare T cell receptor gene-transduced cytotoxic T lymphocytes type 1 applicable to tumor gene cell-therapy
- APPLICATION OF GENETICALLY ENGINEERED TUMOR-SPECIFIC TH1 CELLS TO ADOPTIVE TUMOR IMMUNOTHERAPY
- Blocking of IL-6 signaling pathway prevents CD4^+ T cell-mediated colitis in a T_h17-independent manner
- Distribution of bone mineral density in the proximal tibia in mid-teens
- Treatment strategy for degenerative lumbar scoliosis
- Allylation of Carbonyl Compounds with Allylic Gallium Reagents
- AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade
- AILIM/ICOS signaling induces T-cell migration/polarization of memory/effector T-cells
- Triple-site pacing : a new supported therapy approach for bridge to recovery with a left ventricular assist system in a patient with idiopathic dilated cardiomyopathy
- Pure White Cell Aplasia : Report of the First Case Associated with Primary Biliary Cirrhosis
- Antitumor activity of chimeric immunoreceptor gene-modified Tc1 and Th1 cells against autologous carcinoembryonic antigen-expressing colon cancer cells
- AsialoGM1^+CD8^+ central memory-type T cells in unimmunized mice as novel immunomodulator of IFN-γ-dependent type 1 immunity
- Interleukin-12-responding asialoGM1^+CD8^+ central memory-type T cells as precursor cells for interferon-γ-producing killer T cells
- Relevance of Irinotecan Hydrochloride-Induced Diarrhea to the Level of Prostaglandin E_2 and Water Absorption of Large Intestine in Rats
- Organ motion in image-guided radiotherapy : lessons from real-time tumor-tracking radiotherapy
- Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.
- Dental regenerative therapy : Stem cell transplantation and bioengineered tooth replacement
- A New Device That Protects from Minilaparotomy Wound Infection in Minimally-Invasive Approaches to Colon Cancer
- Prognostic Value of Circulating CA 19-9 in Colorectal Cancer Patients
- A novel tumor-vaccine cell therapy using bone marrow-derived dendritic cell type 1 and antigen-specific T_h1 cells
- 腫瘍微小環境由来TGF-βによって誘導される腫瘍増殖促進免疫制御細胞群の性状とその克服によるがん免疫治療 (特集 腫瘍の免疫回避機構)
- A T_h17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-γ production in order to induce airway hyperresponsiveness
- Potential of Selected Strains of Lactic Acid Bacteria to Induce a Th1 Immune Profile
- Risk Factors for Development of Subaxial Subluxations Following Atlantoaxial Arthrodesis for Atlantoaxial Subluxations in Rheumatoid Arthritis
- New pre-clotting method for fibrin glue in a non-sealed graft used in an LVAD : the KYO method
- P10-28 放射線治療とTh1細胞治療との併用によるマウス肺癌治療効果の増強(ポスター総括10 : 病理2 免疫・血管新生)
- Long-term surgical outcomes of idiopathic spinal cord herniation
- 実地医療と臨床試験 がん特異的免疫治療の進歩と細胞治療の問題点 (特集 進化するがん免疫療法(ワクチン療法,細胞療法,抗体療法))
- Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner
- Successful treatment of cerebral hemorrhage using computed tomography angiography in a patient with left-ventricular-assist device
- Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.
- Structure and Reactivity of Small Ring Compounds. IV. Photochemistry of Spirocyclopropyl Ketones
- ヘルパーT細胞を軸とした癌免疫応答の制御 : 基盤研究から次世代癌ワクチン, H/K-HELPの発見まで
- The cycloaddition of dispiro[2.2.2.2]deca-4,9-diene with the styrene derivatives. The syntheses and spectral properties of the [4.2]paracyclophane derivatives.
- Synthesis of dicyclopropylideneethane and its reaction with some dienophiles.
- The thermal cycloaddition of dispiro[2.2.2.2]deca-4,9-diene to isolated carbon-carbon multiple bonds.
- Preferential Incorporation of a Cyclopropyl .SIGMA. Bond Over an Ethylenic .PI. Bond in the TCNE Cycloaddition of 1,2-Dicyclopropylethylene. Occurrence of the Type-II Reaction in Some Disubstituted Substrates.
- A genome-wide sib-pair linkage analysis of ossification of the posterior longitudinal ligament of the spine
- Sterility of Posterior Elements of the Spine in Posterior Correction Surgery