Partial Replacement of Waxy Cornstarch by Recrystallized Amylose Retards the Development of Insulin Resistance in Rats
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概要
- 論文の詳細を見る
We examined in rats whether or not the prolonged ingestion of recrystallized amylose (RCA) would prevent the development of insulin resistance. Rats were fed on a diet containing waxy cornstarch (WCS) as carbohydrate or a diet containing 30% RCA in place of WCS for 18 wk. Glucose tolerance test (GTT) was conducted at every four weeks. On wk 16, the plasma insulin response as assessed by the area under the curve was lower in the RCA diet group than in the WCS diet group. The fasting plasma insulin level tended to increase over time in both groups, but was lower in the RCA diet group on wk 16. An autopsy revealed that the adipose tissue mass and serum free fatty acid concentrations were significantly higher in the WCS diet group. The results suggest that prolonged ingestion of RCA had the effect of slowing the development of insulin resistance through a lower concentration of serum free fatty acids, presumably due to the prevention of adipocyte hypertrophy.
- 社団法人 日本農芸化学会の論文
- 2006-10-23
著者
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Ito Hiroyuki
Department Of Internal Medicine Division Of Cardiovascular And Respiratory Medicine Akita University
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MORITA Tatsuya
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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SUGIYAMA Kimio
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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Sugiyama Kimio
静岡大学 農 応用生物化学科
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Sugiyama Kimio
静岡大学 農学部応用生物化学
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Morita Tatsuya
静岡大学 農学部応用生物化学
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Morita Tatsuya
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Takeya Koji
Research Center For Basic Science Nisshin Seifun Group Inc.
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Kiriyama Shuhachi
Faculty of Nutritional Sciences, The University of Shizuoka
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杉山 公男
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Sugiyama Kimio
岐阜大学 連合農学研究科
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Morita Tatsuya
岐阜大学 連合農学研究科
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Sugiyama Kimio
Department Of Applied Biochemistry Faculty Of Agriculture Shizuoka University
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杉山 公男
静岡大学 農学部応用生物化学科
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YUTO Shunsuke
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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MOTOI Hirofumi
Research Center for Basic Science, Nisshin Seifun Group Inc.
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YAGISHITA Takahiro
Research Center for Basic Science, Nisshin Seifun Group Inc.
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Yuto Shunsuke
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Motoi Hirofumi
Research Center For Basic Science Nisshin Seifun Group Inc.
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Ito Hiroyuki
Department Of Cardiology Akita University
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Yagishita Takahiro
Research Center For Basic Science Nisshin Seifun Group Inc.
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Ito Hiroyuki
Department Of Anesthesiology Tokyo Medical And Dental University Graduate School Of Medical And Dent
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Ito Hiroyuki
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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SUGIYAMA Kimio
Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University
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