Determinants of Severity in Dilated Cardiomyopathy : The Gap of Tricuspid and Mitral Valve Opening
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概要
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Objectives: The purpose of this study is to analyze factors that influence the gap ofopening timing between the mitral valve (MV) and the tricuspid valve (TV) inpatients with dilated cardiomyopathy (DCM).Background: The DCM patients with heart failure often show shorter left ventricular(LV) isovolumic relaxation time (IRT) and longer right ventricular (RV) IRT, whichmay influence the gap of opening timing between TV and MV.Method: We evaluated consecutive 34 patients with DCM. The time between QRSinitial and TV opening (Q-T time), and that between QRS initial and MV opening (QMtime) were measured by pulsed Doppler recording of each ventricular inflow. Thetime interval between MV and TV opening (M-T time) was determined by subtractingQ-M time from Q-T time. In addition, the other Doppler time intervals including preejectionalperiod, ejection time, IRT were determined. We analyzed the relationbetween Doppler time intervals and factors including NYHA classification and rightsidedcardiac pressure.Result: There is significant relationship (p <0.001) between M-T time and PCWP(r=0.65), and NYHA (rs=0.67), respectively. The Ll IRT determined by subtractionof LV IRT from RV IRT, correlated significantly with M-T time (r=0.83, p<O.OOl),however, the difference between LV and RV in PEP and ET did not correlatedsignificantly with M-T time.Conclusion: The gap of opening timing between TV and MV, determined as M-T time,correlates strongly with LlIRT and also the severity of congestive heart failure in DCMpatients.
著者
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Watanabe Hiroyuki
榊原記念病院 心臓血管外科
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Ito Hiroyuki
Department Of Internal Medicine Division Of Cardiovascular And Respiratory Medicine Akita University
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Tosa Shinya
秋田大学 医学部内科循環器内科学
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Watanabe Hiroyuki
Department Of Cardiovascular And Respiratory Medicine Akita University Graduate School Of Medicine
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Kibira Satoshi
Kibira Medical Clinic
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Izumi Manabu
Department Of Cardiology Research Institute For Brain And Blood Vessels-akita
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Izumi Manabu
Department Of Internal Medicine Division Of Cardiovascular And Respiratory Medicine Akita University
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Nakagawa Masayasu
Department Of Cardiology Akita City Hospital
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Nakagawa Masayasu
Department Of Cardiology Akita City General Hospital
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Kibira Satoshi
2nd Department Or Internal Medicine Akita University School Of Medicine
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Nakagawa Masayasu
The 2nd Department Of Internal Medicine Akita University
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Takahashi Satoru
The Second Department Of Internal Medicine Akita University School Of Medicine Akita.
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Tsuya Hiroyuki
Second Department Of Internal Medicine Akita University
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Sato Tadaya
Division Of Cardiology Akita Medical Center
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Saito Takashi
Second Dept.of Internal Medicine Akita University
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