Effect of Angiotensin Converting Enzyme Inhibitors and β-Blockers on Left Ventricular Remodeling After Coronary Artery Bypass Graft Surgery
スポンサーリンク
概要
- 論文の詳細を見る
Preventing left ventricular (LV) remodeling after coronary artery bypass graft surgery (CABG) is important to avoid long-term congestive heart failure. The present study evaluated the effects of angiotensin converting enzyme inhibitors (ACEIs) and β-blockers on LV remodeling. Twenty-three patients with angina pectoris and 36 with old myocardial infarction underwent CABG. We assessed end diastolic volume index (EDVI), end systolic volume index (ESVI), and ejection fraction (EF) using left ventriculography before and after CABG. Changes in EDVI, ESVI, and EF were studied in the ACEI, β-blocker, and control groups. Although EDVI was reduced in the ACEI group, ESVI and EF improved only slightly, whereas in the group given β-blockers, ESVI was reduced, EF improved, and EDVI was minimally reduced. These results indicate that ACEIs and β-blockers both protect against LV remodeling, although through different mechanisms.
- インターナショナル・ハート・ジャーナル刊行会の論文
著者
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Masaki Nobuyuki
Department of Cardiology, National Defense Medical College
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Maruyama Yoshiaki
Department of Health Promotion, Saitama Medical Center, Saitama Medical University
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Ito Hiroyuki
Department Of Internal Medicine Division Of Cardiovascular And Respiratory Medicine Akita University
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Toyama Kentaro
Department of Cardiology, Kameda Medical Center
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SATO Shunichi
Department of Internal Medicine, School of Medicine Iwate Medical University
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Sasaki Osamu
埼玉医科大学総合医療センター 心臓内科
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Kirimura Masato
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Yuhara Mikio
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Sasaki Osamu
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Kamiyama Tetsuo
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Nishioka Toshihiko
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Yoshimoto Nobuo
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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Yoshimoto Nobuo
Department Of Cardiology Saitama Medical Center Saitama Medical University
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Sato Shunichi
Department Of Cardiology Saitama Medical Center Saitama Medical University
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Toyama Kentaro
Department Of Cardiology Kameda Medical Center
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Masaki Nobuyuki
Department Of Cardiology Saitama Medical Center Saitama Medical University
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Maruyama Yoshiaki
Department Of Health Promotion Saitama Medical Center Saitama Medical University
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Kirimura Masato
Department Of Cardiology Saitama Medical Center Saitama Medical University
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Sasaki Osamu
Department Of Cardiology Uwajima Social Insurance Hospital
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Ito Hiroyuki
Department Of Anesthesiology Tokyo Medical And Dental University Graduate School Of Medical And Dent
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Masaki Nobuyuki
Department of Cardiology, Saitama Medical Center, Saitama Medical University
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