The Prevalence of Subjective Symptoms after Exposure to Arsenic in Drinking Water in Inner Mongolia, China
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概要
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Background: In Inner Mongolia, China, more than 300, 000 people are chronically exposed to arsenic via their drinking water. We have previously reported that the prevalence of arsenical dermatosis was as high as 40% in the Hetao Plain area. However, the association between exposure to arsenic in drinking water and adverse health effects has not been fully examined. The purpose of this study was to examine the association between exposure to arsenic and prevalence of subjective symptoms.Methods: A cross-sectional study was carried out in 431 residents of an arsenic-affected village and 189 residents of an arsenic-free village in 1996. Health-related interviews and physical examinations were conducted. The odds ratio for each subjective symptom was estimated, comparing residents of arsenic-free and affected villages.Results: An arsenic level of 50+ jig/L was found in 90.6% of wells in the arsenic-affected village. Adjusted odds ratios of subjective symptoms, including coughs (odds ratio [OR]=12.8, 95% confidence interval [CI]: 6.4-25.6), stomachaches (OR=5.8, 95% CI: 3.6-9.4), palpitations (OR=3.6, 95% CI: 1.5-8.2), urination problems (OR=14.7, 95% Cl: 3.3-65.5) and spontaneous abortions (OR=2.7, 95% CI: 0.8-8.4), were markedly higher amongst residents of the arsenic-affected village, including those without arsenic dermatosis.Conclusions: The present study shows a high prevalence of subjective symptoms amongst residents of an arsenic-affected village. Symptoms occurred in people with and without arsenic dermatosis. Our findings suggest that symptoms other than dermatosis should be considered when a clinical diagnosis of arsenic toxicosis is made.J Epidemiol 2003;13:211-215.
- 日本疫学会の論文
- 2003-07-01
著者
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FUJINO Yoshihisa
Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occu
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Li Yanhong
Inner Mongolia Center For Endemic Disease Control And Research
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GUO Xiaojuan
Department of Preventive Medicine, School of Public Health, Wenzhou Medical College
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WU Kegong
Center for Endemic Disease Control and Research of Inner Mongolia
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Yoshimura Takesumi
Department Of Clinical Epidemiology Institute Of Industrial Ecological Science University Of Occupat
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Yoshimura Takesumi
Fukuoka Institute Of Health And Environmental Sciences Former Affiliation : Department Of Clinical E
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Yoshimura Takesumi
University Of Occupational And Environmental Health
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Sun Zhiming
Station For Hygiene Prevention Of Wuyuan County In Inner Mongolia
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Guo Xiaojuan
Department Of Preventive Medicine School Of Public Health Wenzhou Medical College
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Fujino Yoshihisa
Department Of Preventive Medicine Annd Community Health School Of Medicine University Of Occupationa
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GUO Xiaojuan
Inner Mongolia Center for Endemic Disease Control and Research
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CHAI Jinshan
Inner Mongolia Center for Endemic Disease Control and Research
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WU Kegong
Inner Mongolia Center for Endemic Disease Control and Research
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XIA Yajuan
Inner Mongolia Center for Endemic Disease Control and Research
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LV Jiangang
Station for hygiene prevention of Wuyuan County in Inner Mongolia
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Fujino Yoshihisa
産業医科大学 公衆衛生学
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Yoshimura Takesumi
Department of Clinical Epidemiology
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