Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process

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概要

• 論文の詳細を見る

• This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel ``systematic evolution of ligands by exponential enrichment'' (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during the SELEX process. The proposed device with an optimally designed hydraulic resistance-balanced channel network could be feasible and utilized as a multiplex selection module for a parallel SELEX process.

• 2011-06-25

著者

• Kim So

  Department Of Cardiology College Of Medicine Catholic University Of Daegu

• Lee Sang

  Department Of Advanced Materials Science And Engineering Mokpo National University

• Laurell Thomas

  Department Electrical Measurement Lund Intitute Of Technology Lund University

• Kim Tae

  Department Of Anesthesia And Pain Medicine School Of Medicine Pusan National University

• Laurell Thomas

  Department of Electrical Measurements, Lund University, Lund 22184, Sweden

• Ahn Ji-Young

  Department of Biomedical Engineering, Dongguk University, Seoul 100-715, Korea

• Jeong Ok

  Department of Biomedical Engineering, Inje University, Gimhae, Gyungnam 621-749, Korea

• Lee Sang

  Department of Electrical Measurements, Lund University, Lund 22184, Sweden

• LEE Sang

  Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University

• Kim Tae

  Department of Biomedical Engineering, Inje University, Gimhae, Gyungnam 621-749, Korea

• Kim So

  Department of Biomedical Engineering, Dongguk University, Seoul 100-715, Korea

• Kim Tae

  Department of Advanced Materials Engineering, Sungkyunkwan University, Suwon, Gyeonggi 440-746, Republic Korea

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