Dielectric Relaxation Analysis of Single-Stranded DNA in Liquid Crystals
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概要
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Since liquid crystals have found wide use in liquid crystal displays, we try to apply liquid crystals to biotechnology. The purpose of this study is to describe the physical properties of the biopolymer DNA in regard to electrooptics. Synthetic oligonucleotide molecules were dispersed in a nematic liquid crystal (NLC). The ICP analyses showed that all of the oligonuleotide molecules added dispersed in the NLC. This sample was injected into the twisted nematic liquid crystal display cells, and then we measured its dielectric properties. The NLC doped with oligonucleotide molecules exhibited dielectric relaxation characteristics, depending on the concentration of oligonucleotide molecules. After analyzing this effect by using the equivalent circuit model, we found a difference in electrical conductivity between Watson–Crick base pairs (AT and GC). This result suggests that the difference might have contributed to the existence of a functional group involved in the hydrogen-bond interaction.
- 2010-08-25
著者
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Abe Masahiko
Department Of Internal Medicine Hokkaido Prefectural Haboro Hospital
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Furue Hirokazu
Department Of Electronics And Computer Science Faculty Of Science And Engineering Science University
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Kobayashi Shunsuke
Liquid Crystal Institute And Graduate School Of Engineering Science Tokyo University Of Science
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Inoue Masaru
Toyo Corporation
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Sakaguchi Kengo
Department Of Applied Biological Science Faculty Of Science And Technology Science University Of Tok
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Itagaki Masayuki
Department Of Chemical Industry Science University Of Tokyo
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Uchiyama Yukinobu
Department Of Applied Biological Science Faculty Of Science And Technology Tokyo University Of Scien
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Nakabayashi Tadashi
Department of Applied Biological Science, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Inoue Masaru
TOYO Corporation, 1-6 Yaesu 1-chome, Chuo, Tokyo 103-8284, Japan
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Itagaki Masayuki
Department of Industrial Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Iwabata Kazuki
Department of Applied Biological Science, Tokyo University of Science, Noda, Chiba 278-8510, Japan
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Sakai Hideki
Department of Industrial Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Taki Shingo
Department of Industrial Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Ando Kazuyuki
Department of Industrial Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Sakaguchi Kengo
Department of Applied Biological Science, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Uchiyama Yukinobu
Department of Applied Biological Science, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Iwabata Kazuki
Department of Applied Biological Science, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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Furue Hirokazu
Department of Materials Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
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