Lung Cancer Complicated with IgG4-related Disease of the Lung
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概要
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Few have reported a concomitant malignant neoplasm with immunoglobulin G4 (IgG4)-related diseases. We describe a case of lung cancer and gastric cancer accompanied with IgG4-related disease. A 78-year-old man had an area of ground-glass opacity with central collapse in right upper lobe and a gastric cancer. The patient underwent a right upper lobectomy following a gastrectomy for the gastric cancer. Histological examination of the resected lung specimen revealed a lepidic pattern of an adenocarcinoma and a large amount of plasmacyte infiltration around the tumor. In immunohistochemical findings, the plasmacytes were stained for IgG4. Therefore, the lung tumor was considered to have associated with IgG4-related interstitial lesions.
著者
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Honma Koichi
Department Of Anatomic And Diagnostic Pathology Dokkyo Medical University
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Kobayashi Satoru
Department Biology Tokyo Metropolitan Institute Of Gerontology
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Chida Masayuki
Department Of General Thoracic Surgery Dokkyo Medical University
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INOUE Takashi
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
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OYAIZU Takeshi
Department of General Thoracic Surgery, Dokkyo Medical University
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HAYAMA Makio
Department of General Thoracic Surgery, Dokkyo Medical University
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NAKAZATO Yoshimasa
Department of Anatomic and Diagnostic Pathology, Dokkyo University School of Medicine
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Honma Koichi
Department of Anatomic and Diagnostic Pathology, Dokkyo Medical University
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Nakazato Yoshimasa
Department of Anatomic and Diagnostic Pathology, Dokkyo Medical University
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Hayama Makio
Department of General Thoracic Surgery, Dokkyo Medical Uni versity, School of Medicine, Mibu, Tochigi, Japan
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Oyaizu Takeshi
Department of General Thoracic Surgery, Dokkyo Medical Uni versity, School of Medicine, Mibu, Tochigi, Japan
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