Incidence of Acute Exacerbation of Interstitial Pneumonia in Operated Lung Cancer : Institutional Report and Review
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概要
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Purpose: Several small studies have reported that acute exacerbation (AE) of idiopathic interstitial pneumonia (IIP) can occur after lung resection for patients with non-small cell lung cancer, though the incidence rate is unclear. Methods: We examined our institutional data and performed a search of the MEDLINE database for publications regarding AE of IIP following surgery for lung cancer. Studies reporting the incidence rates of IIP and AE were included. Results: Eleven studies including our institutional data were determined to be eligible. Seven studies designated the incidence of IIP. Of 4749 patients (from 7 studies) who underwent lung resection for NSCLC, 277 had IIP, for an incidence rate of 5.8% (range 1.1%–11.7%). Eleven studies designated the incidence of AE from IIP patient, 67 (15.8%) of 424 IIP patients (from 11 studies) developed AE after surgery, of whom 38 (56.7%) died during the postoperative course. Conclusion: Coexistent IIP in patients with lung cancer increases the risk of lung cancer surgery. Furthermore, AE of IIP may be a major cause of operation-related death.
- 2012-08-01
著者
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Karube Yoko
Department Of Thoracic Surgery Dokkyo University School Of Medicine
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Kobayashi Satoru
Department Biology Tokyo Metropolitan Institute Of Gerontology
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Ishihama Hiromi
Department Of Cardiothoracic Surgery Dokkyo University School Of Medicine
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Tamura Motohiko
Department Of General Thoracic Surgery Dokkyo Medical University
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Chida Masayuki
Department Of General Thoracic Surgery Dokkyo Medical University
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OYAIZU Takeshi
Department of General Thoracic Surgery, Dokkyo Medical University
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HAYAMA Makio
Department of General Thoracic Surgery, Dokkyo Medical University
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KARUBE Yoko
Department of General Thoracic Surgery, Dokkyo Medical University
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Oyaizu Takeshi
Department of General Thoracic Surgery, Dokkyo Medical Uni versity, Tochigi, Japan
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