Urgent Endarterectomy Using Pretreatment With Free Radical Scavenger, Edaravone, and Early Clamping of the Parent Arteries for Cervical Carotid Artery Stenosis With Crescendo Transient Ischemic Attacks Caused by Mobile Thrombus and Hemodynamic Cerebral Is

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概要

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• A 68-year-old man with left cervical internal carotid artery stenosis suffered crescendo transient ischemic attacks caused by mobile thrombus detected by carotid echography and secondary impairment of cerebral hemodynamic reserve demonstrated by positron emission tomography. Urgent carotid endarterectomy (CEA) was performed following pretreatment with edaravone and early clamping of the carotid arteries without intraluminal shunting. The postoperative course was uneventful, and postoperative magnetic resonance imaging and single-photon emission computed tomography revealed no new cerebral ischemic lesions and no findings of cerebral hyperperfusion, respectively. The risks associated with CEA are higher for patients with evolving stroke or crescendo transient ischemic attacks than that for patients with stable disease. This case demonstrates that urgent endarterectomy for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombi and hemodynamic cerebral ischemia can be successfully performed following pretreatment with edaravone and early clamping of the carotid arteries.

• 社団法人 日本脳神経外科学会の論文
• 2007-03-15

著者

• OGAWA Akira

  Department of Neurosurgery, Iwate Medical University School of Medicine

• OGASAWARA Kuniaki

  Department of Neurosurgery, Iwate Medical University School of Medicine

• INOUE Takashi

  Department of Neurosurgery, School of Medicine, Iwate Medical University

• Ogasawara Kuniaki

  岩手医科大学 脳神経外科

• Ogasawara Kuniaki

  Department Of Neurosurgery Iwate Medical University

• Kobayashi Masakazu

  Department of Cardiology, Nagoya University Graduate School of Medicine

• SAITO Hideo

  Department of Urology, Tohoku University Hospital

• Kobayashi Masakazu

  Departmdepartment Of Cardiology Nagoya University Graduate School Of Medicine

• Ogawa Akira

  Department Of Neurosurgery Iwate Medical University

• SUGA Yasunori

  Department of Neurosurgery, Iwate Medical University

• KOMORIBAYASHI Nobukazu

  Department of Neurosurgery and Cyclotron Research Center, Iwate Medical University

• Kobayashi Masakazu

  Department Of Neurosurgery Iwate Medical University

• Saito Hideo

  Department Of Chemistry Graduate School Of Pure And Applied Sciences University Of Tsukuba

• Saitoh Hideo

  Department Of Neurosurgery Iwate Medical University

• Suga Yasunori

  Department Of Neurosurgery Iwate Medical University

• Ogawa Akira

  Department Of Biochemistry Gunma University Graduate School Of Medicine

• Ogawa Akira

  Department Of Neurosurgery Iwate Medical University School Of Medicine

• Komoribayashi Nobukazu

  Department Of Neurosurgery And Cyclotron Research Center Iwate Medical University

• Ogawa Akira

  Department Of Applied Chemistry Graduate School Of Engineering The University Of Tokyo

• Ogawa Akira

  Department Of Neurosurgery Central Clinical Laboratory Iwate Medical University

• Inoue Takashi

  Department Of Neurosurgery Iwate Medical University

• Inoue Takashi

  Department Of Neurosurgery Kohnan Hospital

• Inoue Takashi

  Department Of Anatomy Kyoto Prefectural University Of Medicine

• Inoue Takashi

  Department Of Agricultural Engineering Faculty Of Agriculture Hokkaido University

• OGAWA Akira

  Department of Neurosurgery, Iwate Medical University

• OGASAWARA Kuniaki

  Department of Neurosurgery, Iwate Medical University

• INOUE Takashi

  Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo

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