Resolution of Gelatinous Bone Marrow Transformation Following Hormone Replacement Therapy in a Patient with Primary Insufficiency of the Adrenal and Thyroid Glands
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概要
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A 59-year-old man with recurrent oral cancer presented with severe pancytopenia, hyponatremia and hypoglycemia. Endocrine testing showed a partial primary adrenal insufficiency and primary hypothyroidism. The bone marrow biopsy showed a gelatinous transformation with hypocellularity and fat atrophy. His pancytopenia, hyponatremia and hypoglycemia resolved following treatment with corticosteroids and thyroid hormone replacement therapy. The follow-up bone marrow biopsy demonstrated a resolution of the gelatinous transformation. This case is a rare example of a patient with a primary insufficiency of the adrenal and thyroid glands that is associated with gelatinous bone marrow transformation (GMT). The GMT was resolved through the admimistration of corticosteroids and thyroid hormone replacement therapy.
著者
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Yamamoto Koji
Department of Internal Medicine, Hattori Memorial Hospital
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Matsuzawa Yuji
Department Of 2nd Internal Medicine Faculty Of Medicine Oaka University
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Fujita Shigeki
Department Of Pathology Osaka Police Hospital
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Ujiie Hidetoshi
Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Osaka University
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Saisho Kenji
Department Of Endocrinology And Metabolism Sumitomo Hospital
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Obata Yoshinari
Department Of Endocrinology And Metabolism Sumitomo Hospital
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Takahi Yasumitsu
Department Of Endocrinology And Metabolism Sumitomo Hospital
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Tamba Sachiko
Department Of Endocrinology And Metabolism Sumitomo Hospital
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HATTORI Kenji
Department of Material Physics, Faculty of Engineering Science, Osaka University
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YAMADA Yuya
Department of Biomaterials Science, Osaka University Graduate School of Dentistry
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Yamato Akiyuki
Department of Otorhinolaryngology, Head and Neck Surgery, Sumitomo Hospital, Japan
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Kyo Mitsuaki
Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan
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