Mortality Among Japanese With a History of Kawasaki Disease: Results at the End of 2009
スポンサーリンク
概要
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Background: The long-term outcomes of Kawasaki disease (KD) are unknown.<BR>Methods: Fifty-two collaborating hospitals collected data on all patients who had received a new definite diagnosis of KD between July 1982 and December 1992. Patients were followed until December 31, 2009 or death. Standardized mortality ratios (SMRs) were calculated based on Japanese vital statistics data.<BR>Results: Of the 6576 patients enrolled, 46 (35 males and 11 females) died (SMR: 1.00; 95% CI: 0.73–1.34). Among persons without cardiac sequelae, SMRs were not high after the acute phase of KD (SMR: 0.65; 95% CI: 0.41–0.96). Among persons with cardiac sequelae, 13 males and 1 female died during the observation period (SMR: 1.86; 95% CI: 1.02–3.13).<BR>Conclusions: In this cohort, the mortality rate among Japanese with cardiac sequelae due to KD was significantly higher than that of the general population. In contrast, the rates for males and females without sequelae were not elevated.
著者
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Yashiro Mayumi
Department of Public Health, Jichi Medical University
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Kotani Kazuhiko
Department of Public Health, Jichi Medical University
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Kotani Kazuhiko
Department Of Clinical Laboratory Medicine Jichi Medical University
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Uehara Ritei
Department Of Pediatrics Jikei University School Of Medicine
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Yashiro Mayumi
Department Of Public Health Jichi Medical School
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Nakamura Yosikazu
Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School
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Aso Eiko
Department Of Public Health Jichi Medical University
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Aoyama Yasuko
Department Of Public Health Jichi Medical University
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Tsuboi Satoshi
Department Of Electrical And Electronic Engineering Kobe University
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Yanagawa Hiroshi
Department Of Applied Chemistry Keio University
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Kojo Takao
Department of Public Health, Jichi Medical University
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