Relationship between the Cumulative Incidence of Kawasaki Disease and the Prevalence of Electrocardiographic Abnormalities in Birth-Year Cohorts
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概要
- 論文の詳細を見る
Background: Kawasaki disease (KD) causes systemic vasculitis and coronary aneurysms. It frequently results in electrocardiographic (ECG) abnormalities of short duration. Cardiac sequelae persist beyond the acute stage in a few patients. There are many areas to be investigated concerning the effects on the vascular system of patients suffering from KD and its sequelae.Methods: The cumulative incidences of KD and its cardiac sequelae were calculated in birth-year cohorts, using data obtained from KD nationwide surveys. The results were compared with the prevalence of ECG abnormalities detected in cardiac examinations conducted at primary and secondary schools for each birth-year cohort. This comparison allowed observation of relationships in these trends for each birth-year cohort.Results: The cumulative incidence of late-stage cardiac sequelae gradually declined. However, there were increases in the cumulative incidence of ECG abnormalities and in the cumulative incidences of KD and acute-stage cardiac disorders related to KD.Conclusions: The results suggest that even among children without late cardiac sequelae, KD can have a persistent effect on the cardiovascular system. It thus appears necessary to extend clinical observation of children with a history of KD, even if they developed only acute-stage cardiac lesions.
- 日本疫学会の論文
- 2010-11-01
著者
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柳川 洋
Department Of Public Health Jichi Medical University
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Nakamura Y
Department Of Public Health Jichi Medical University
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Nakamura Y
Human Genome Center Institute Of Medical Science University Of Tokyo
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Nagane Yutaka
東京大学医科学研究所ヒトゲノム解析センター
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Kario Kazuomi
米国
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中村 好一
Department of Public Health, Jichi Medical University
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Yashiro Mayumi
Department Of Public Health Jichi Medical School
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Yanagawa H
Department Of Public Health Jichi Medical University
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Nakamura Yasuyuki
Heart Rhythm Center Department Of Cardiovascular Medicine Shiga University Of Medical Science
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Nakamura Yosikazu
Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School
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Nakamura Y
Division Of Epidemiology Miyagi Cancer Center Research Institute
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Murakami Yoshitaka
Fac. Of Healthcare Kiryu Univ.
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Niwa Yoshimitsu
自治医科大学 公衆衛生学
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Nakamura Yusuke
Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science University Of Toky
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Kotani Kazuhiko
Department Of Public Health Jichi Medical University
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Nakamura Yusuke
Univ. Tokyo Tokyo Jpn
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Nakamura Yasuyuki
滋賀医科大学 循環器内科
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Nakamura Yasuyuki
Division Of Cardiology Department Of Medicine Shiga University Of Medical Science
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Yanagawa Hiroshi
Department Of Applied Chemistry Keio University
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Nagatani Yukihiro
Heart Rhythm Center Department Of Cardiovascular Medicine Shiga University Of Medical Science
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KAWAI Kunio
Kouno Clinic
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Nagatani Yukihiro
滋賀医科大学 循環器内科
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中村 好一
Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science University Of Toky
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Nonomura Yasuhiro
Department Of Neuropsychiatry Osaka Medical College
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