The Clinical Characteristics of Two Anti-OJ (Anti-Isoleucyl-tRNA Synthetase) Autoantibody-Positive Interstitial Lung Disease Patients with Polymyositis/Dermatomyositis

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概要

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• We herein report the clinical and laboratory characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis (PM/DM). We compared these characteristics with previously published findings. Previous reports and our present cases show that anti-OJ autoantibody-positive interstitial lung disease (ILD) patients with PM/DM lack the manifestations of Raynaud's phenomenon and sclerodactyly and show good prognoses and responses to glucocorticoid therapy. These results indicate that the presence of anti-OJ autoantibodies may be useful for predicting the prognosis of ILD and its clinical course in PM/DM patients.

著者

• Mimori Tsuneyo

  Department Of Internal Medicine Keio University School Of Medicine

• Fujii Takao

  Department Of Applied Life Science Faculty Of Biotechnology And Life Science Sojo University

• Ubukata Satoshi

  Department of Cardiology, Jichi Medical School

• Ishida Tadashi

  Department Of Hematology And Oncology Graduate School Of Medicine Kyoto University

• Fukuda Yasushi

  Department Of Humanities Kyushu Lutheran College

• ARITA Machiko

  Department of Respiratory Medicine, Kurashiki Central Hospital

• Nakagawa Hiroaki

  Department Of Internal Medicine Kyoto Prefectural University Of Medicine

• Kunimasa Kei

  Department Of Respiratory Medicine Kurashiki Central Hospital

• Nakazawa Takashi

  Department Of Chemistry Faculty Of Science Nara Women's University

• Konishi Satoshi

  Department Micro System Technology Faculty Of Science And Engineering Ritsumeikan University

• TANAKA Maki

  Department of Internal Medicine, Takasago Municipal Hospital

• Tanaka Maki

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Fukuda Yasushi

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Tsubouchi Kazuya

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Korogi Yohei

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Saigusa Mika

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Ubukata Satoshi

  Department of Respiratory Medicine, Kurashiki Central Hospital, Japan

• Mimori Tsuneyo

  Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Japan

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