Long-term Clinical Course of a Patient with Anti PL-12 Antibody Accompanied by Interstitial Pneumonia and Severe Pulmonary Hypertension
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概要
- 論文の詳細を見る
We report a case of a patient with anti PL-12 antibody accompanied by interstitial pneumonia and severe pulmonary hypertension. At first presentation, hyperkeratotic skin lesions were found, although the diagnosis of CVD was not conclusive. Lung histology showed diffuse fibrosing interstitial pneumonia predominantly in the subpleural regions. During the seven-year follow-up period, severe pulmonary hypertension developed, although the progression of lung fibrosis was relatively limited. Anti-PL12 antibody was detected, and therefore the patient was diagnosed as having antisynthetase syndrome. Lung histology and pulmonary arteriogram suggested that vascular involvement of the disease contributed to the development of severe pulmonary hypertension.
- 社団法人 日本内科学会の論文
- 2005-04-01
著者
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HANDA Tomohiro
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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MISHIMA Michiaki
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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Mishima Michiaki
The Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Mimori Tsuneyo
Department Of Rheumatology And Clinical Immunology Graduate School Of Medicine Kyoto University
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NAGAI Sonoko
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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Kitaichi Masanori
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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Nagao Taishi
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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KAWABATA Daisuke
Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine
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Nagao Taishi
The Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Nagai Sonoko
The Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Nagai Sonoko
Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Izumi Takateru
Kyoto Central Clinic
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TAKEMURA Masaya
Department of Respiratory Medicine, Kyoto University
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Handa Tomohiro
The Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Mimori Tsuneyo
Department Of Internal Medicine Keio University School Of Medicine
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Mishima Michiaki
Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Kitaichi Masanori
The Laboratory Of Anatomic Pathology Kyoto University Hospital
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Kitaichi Masanori
Department Of Pathology Kinki-chuo Chest Medical Center
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Takemura Masaya
Department Of Respiratory Medicine Graduate School Of Medicine Kyoto University
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Kawabata Daisuke
Department Of Rheumatology And Clinical Immunology Graduate School Of Medicine Kyoto University
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Takemura Masaya
Department Of Epidemiology And Healthcare Research Kyoto University Graduate School Of Medicine And
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Kitaichi Masanori
Department of Laboratory Medicine and Pathology National Hospital Organization Kinki-Chuo Chest Medical Center
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