Antisynthetase Syndrome Associated with Sarcoidosis
スポンサーリンク
概要
- 論文の詳細を見る
A 30-year-old man complained of polyarthralgia and fatigue. The clinical findings and laboratory data included myositis, polyarthritis, interstitial pneumonia, Raynauds phenomenon, mechanics hand, and anti PL-7 antibody (threonyl-tRNA synthetase antibody). All of these signs were consistent with antisynthetase syndrome. His chest radiograph revealed bilateral hilar lymphadenopathy. Biopsy specimens from his mediastinal lymph node and muscle showed noncaseating epithelioid cell granulomas. Lung histology revealed nonspecific interstitial pneumonia. Antisynthetase syndrome associated with sarcoidosis was diagnosed. Interstitial pneumonia in this patient responded well to high-dose corticosteroid therapy.
著者
-
Mimori Tsuneyo
Department Of Internal Medicine Keio University School Of Medicine
-
Kawabata Yoshinori
Department Of Thoracic Surgery And Pathology Saitama Cardiovascular And Respiratory Center
-
MORIGUCHI Masato
Clinical Department of Internal Medicine, Jichi Medical School, Omiya Medical Center
-
Kobayashi Shio
Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University
-
Asanuma Yu
Clinical Department of Internal Medicine, Jichi Medical School Omiya Medical Center
-
Koichihara Reiko
Clinical Department of Internal Medicine, Jichi Medical School Omiya Medical Center
-
Koyama Shinichiro
Clinical Department of Internal Medicine, Jichi Medical School Omiya Medical Center
-
Koyama Shinichiro
Clinical Department of Inernal Medicine, Jichi Medical University, Omiya Medical Center
関連論文
- Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells
- Amelioration of experimental arthritis by a calpain-inhibitory compound : regulation of cytokine production by E-64-d in vivo and in vitro
- Characterization of anticytoplasmic antibodies in patients with systemic autoimmune diseases
- Efficacy and safety of mizoribine for the treatment of Sjogren's syndrome : a multicenter open-label clinical trial
- Long-term Clinical Course of a Patient with Anti PL-12 Antibody Accompanied by Interstitial Pneumonia and Severe Pulmonary Hypertension
- Severe hypertention associated with multiple intrarenal microaneurysms in a patient with systemic lupus erythematosus and antiphospholipid antibodies
- Potential preventive effects of follistatin-related protein/TSC-36 on joint destruction and antagonistic modulation of its autoantibodies in rheumatoid arthritis
- Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus
- A case of late-onset polymyositis with autoantibodies to the signal recognition particle
- Clinical Significance of Anti-CCP Antibodies in Rheumatoid Arthritis
- C4B Deficiency Associated with Membranoproliferative Glomerulonephritis
- Incidence of Pulmonary Hypertension and Its Clinical Relevance in Patients with Interstitial Pneumonias: Comparison between Idiopathic and Collagen Vascular Disease Associated Interstitial Pneumonias
- Sensorimotor polyneuropathy as an initial clinical manifestation of sarcoidosis
- Periodic fever and erythema nodosum associated with MDS with trisomy 8 : report of two cases and review of the literature
- Two cases of late-onset drug-induced lupus erythematosus caused by ticlopidine in elderly men
- Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population
- Isolation of Candida Species is an Important Clue for Suspecting Gastrointestinal Tract Perforation as a Cause of Empyema
- Ku Antigen Binds to Alu Family DNA^1
- Aseptic meningitis in mixed connective tissue disease : cytokine and anti-U1RNP antibodies in cerebrospinal fluids from two different cases
- Upper Lobe-Dominant Pulmonary Fibrosis Showing Deposits of Hard Metal Component in the Fibrotic Lesions
- Pathological Findings and Pulmonary Dysfunction after Acute Respiratory Distress Syndrome for 5 Years
- Spontaneous Hemorrhage of a Thymic Cyst in an Adult : Report of a Case
- Successful Treatment of Primary Sjögrens Syndrome with Chronic Natural Killer Lymphocytosis by High-Dose Prednisolone and Indomethacin Farnesil
- Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
- A novel clinical entity, IgG4-related disease (IgG4RD) : general concept and details
- A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations
- Antisynthetase Syndrome Associated with Sarcoidosis
- Pulmonary Capillaritis in Wegener's Granulomatosis Detected Via Transbronchial Lung Biopsy
- Serum IgG levels demonstrate seasonal change in connective tissue diseases : a large-scale, 4-year analysis in Japanese
- The Clinical Characteristics of Two Anti-OJ (Anti-Isoleucyl-tRNA Synthetase) Autoantibody-Positive Interstitial Lung Disease Patients with Polymyositis/Dermatomyositis
- NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA
- Clinical Features and Treatment of Multicentric Castleman's Disease : A Retrospective Study of 21 Japanese Patients at a Single Institute
- Allergic Bronchopulmonary Aspergillosis with Repeated Isolation of Nontuberculous Mycobacteria
- Leukoencephalopathy with Cognitive Impairment following Tocilizumab for the Treatment of Rheumatoid Arthritis (RA)
- Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis
- Clinical Features and Treatment of Multicentric Castleman's Disease : A Retrospective Study of 21 Japanese Patients at a Single Institute
- Concomitant iguratimod therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate : a randomized, double-blind, placebo-controlled trial