Ingestion of Cinnamaldehyde, a TRPA1 Agonist, Reduces Visceral Fats in Mice Fed a High-Fat and High-Sucrose Diet
スポンサーリンク
概要
- 論文の詳細を見る
Cinnamaldehyde (CNA), a pungent compound in cinnamon or dried bark of cassia, is a TRPA1 agonist. The effect of 0.1-1.0% CNA on pair-fed mice with high fat and high sucrose (HFS) diet for 1 mo was investigated. The total food intake was similar in the mice fed control and CNA diets, but the body weight showed a tendency to be lower in CNA-fed mice than in control mice. By adding CNA at 0.1, 0.5, and 1.0% concentrations, the weight of the mesenteric adipose tissue decreased significantly, and there was a tendency foward lower perirenal and epididymal adipose tissue weights compared to the control. No differences were found in any blood component measured. UCP1 protein levels in the interscapular brown adipose tissue were higher in the 0.5 and 1.0% CNA groups than in the HSF group, as shown by Western blotting. Collectively, these data show that the addition of CNA diminishes visceral fat deposition in HFS diet-fed mice, in part by stimulating interscapular brown adipose tissue.
著者
-
Iwasaki Yusaku
Graduate School Of Nutritional And Environmental Sciences Univ. Of Shizuoka
-
Tamura Yasuko
Graduate School Of Nutritional And Environmental Sciences University Of Shizuoka
-
NARUKAWA Masataka
Graduate School of Nutritional and Environmental Sciences, University of Shizuoka
-
NARUKAWA Masataka
Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
WATANABE Tatsuo
Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka
関連論文
- Change in Taste Sensitivity to Sucrose Due to Physical Fatigue
- Galangal Pungent Component, 1′-Acetoxychavicol Acetate, Activates TRPA1
- Activation of TRPV1 and TRPA1 by Black Pepper Components
- Pungent Qualities of Sanshool-Related Compounds Evaluated by a Sensory Test and Activation of Rat TRPV1
- TRPA1 Agonists—Allyl Isothiocyanate and Cinnamaldehyde—Induce Adrenaline Secretion
- Newly Synthesized Oleylgingerol and Oleylshogaol Activate TRPV1 Ion Channels
- Capsaicinol : Synthesis by Allylic Oxidation and Its Effect on TRPV1-Expressing Cells and Adrenaline Secretion in Rats
- Capsinoid Is Biosynthesized from Phenylalanine and Valine in a Non-Pungent Pepper, Capsicum annuum L. cv. CH-19 Sweet
- Adiposity Suppression Effect in Mice Due to Black Pepper and Its Main Pungent Component, Piperine
- Activation of TRPV1 and TRPA1 by Black Pepper Components
- Influence of Prolonged Exercise on Sweet Taste Perception
- Galangal Pungent Component, 1'-Acetoxychavicol Acetate, Activates TRPA1
- L-Theanine Elicits an Umami Taste with Inosine 5'-Monophosphate
- TRPA1 Agonists-Allyl Isothiocyanate and Cinnamaldehyde-Induce Adrenaline Secretion
- TRPV1 Agonist Monoacyglycerol Increases UCP1 Content in Brown Adipose Tissue and Suppresses Accumulation of Visceral Fat in Mice Fed a High-Fat and High-Sucrose Diet
- Synthesis of Stable Isotope-Labeled Precursors for the Biosyntheses of Capsaicinoids, Capsinoids, and Capsiconinoids
- Ingestion of Cinnamaldehyde, a TRPA1 Agonist, Reduces Visceral Fats in Mice Fed a High-Fat and High-Sucrose Diet
- Nerve and Behavioral Responses of Mice to Various Umami Substances
- Ingestion of Cinnamaldehyde, a TRPA1 Agonist, Reduces Visceral Fats in Mice Fed a High-Fat and High-Sucrose Diet
- Activation of the hTAS2R14 Human Bitter-Taste Receptor by (−)-Epigallocatechin Gallate and (−)-Epicatechin Gallate
- Evaluation of the Suppressive Effect on Bitter Taste of Gluconate