Influence of beta-adrenergic blocking agent on the circadian rhythm of blood pressure in patients with essential hypertension.
スポンサーリンク
概要
- 論文の詳細を見る
Ambulatory blood pressure (BP) was obtained before and 2 months after the initiationof atenolol therapy in subjects with mild essential hypertension to determine whether theadministration of atenolol, a beta adrenoreceptor blocking agent, modifies the circadianpattern of blood pressure. BP was measured by a non-invasive automatic device with a15-min interval during a 24-hr period, and was analyzed by fitting of power-normal transformationmodel (PNT model).<BR>The circadian pattern of systolic BP in 4 patients out of 6 and diastolic BP in 2 out 6were modified and the amplitude of systolic BP was reduced with a prolonged atenololtherapy.<BR>These findings indicate that the circadian pattern of BP is modified by chronic atenololtherapy, which is caused by the suppression of the elevation of BP during the daytime
- 一般社団法人 日本臨床薬理学会の論文
著者
-
海老原 昭夫
大分医科大学医学部臨床薬理学
-
藤村 昭夫
大分医科大学臨床薬理学教室
-
熊谷 雄治
大分医科大学臨床薬理学教室
-
杉本 孝一
大分医科大学臨床薬理
-
藤村 昭夫
大分医科大学臨床薬理
-
熊谷 雄治
大分医科大学臨床薬理
関連論文
- 健常成人におけるバルプロ酸反復投与時の体内動態
- ヒスタミンH_2受容体遮断薬
- Dosage regimen for ranitidin in renal impairment. (2). Multiple oral dose studies.
- A compartment model for a sustained release preparation with zero-order release.
- Assessment of a simple method for acetylator phenotyping with caffeine.
- Polymorphous mode of caffeine metabolism in the Japanese poeple. On genotypes.
- Pharmacokinetics, pharmacodynamics, and safety of bevantolol, a new .BETA.1-selective .BETA.-adrenoceptor antagonist, in Japanese healthy volunteers.
- Clinical pharmacological studies on a new .BETA.1 selective .BETA.-blocker, bevantolol.
- Population pharmacokinetics of theophylline in patients with infantile bronchial asthma.
- Clinical pharmacology of ibopamine. (1). Safety and pharmacological actions after single and multiple oral doses in Japanese healthy subjects.
- Pharmacokinetics of beta-methyldigoxin.
- Clinical pharmacology of nitrendipine - Single- and multiple-dose study in Japanese healthy subjects.:Single- and Multiple-Dose Study in Japanese Healthy Subjects
- Pharmacokinetics of ketoprofen sustained-releasing preparation (RPY-001) in Japanese normal adult persons.
- Pharmacodynamic and pharmacological effects of nipradilol (K-351) in healthy volunteers. Comparison with propranolol.:Comparison with Propranolol
- Influence of beta-adrenergic blocking agent on the circadian rhythm of blood pressure in patients with essential hypertension.
- Clinical phase I studies of a new antiemetic drug, SN-307 (ondansetron).
- タイトル無し
- Pharmacokinetics of digoxin in patients with duchenne muscular dystrophy.
- Dosage regimen for ranitidine in renal impairment.
- Effect of premedication term and premedication dose of diltiazem on pharmacokinetics of nifedipine.
- Effect of diltiazem on pharmacokinetics of theophylline.
- Pharmacodynamics and pharmacological actions of MPC-1304, a Ca antagonist, in healthy adults.
- Effects of angiotensin II converting enzyme inhibitor enarapril on autonomic nervous system.
- Pharmacodynamic and pharmacological effects of MPC-1304, a new calcium channel blocker, in healthy subjects. Results of multiple oral administration.:Results of Multiple Oral Administration
- Effects of MPC-1304 on blood flow of the finger tip.
- Pharmacokinetics and pharmacodynamic effects of sustained release formulation of urapidil (BKU) in healthy subjects. Results of repeated oral administration.:Results of Repeated Oral Administration
- タイトル無し
- Clinical pharmacology of a new antiplatelet drug, KBT-3022. Results of single administration in Japanese healthy adults.
- Clinical pharmacology of a new antiplatelet drug, KBT-3022. Studies on repeated administration in healthy adults.
- Effect of beta-blockers on circadian rhythm of blood pressure in patients with essential hypertension.
- Clinical pharmacology of ibopamine. (2). Pharmacokinetics after single and multiple oral administration in healthy Japanese subjects.
- Circadian variation in blood pressure in case of administration of various types of hypotensive drugs.
- Pharmacodynamic and pharmacological effects of MPC-1304, a new calcium channel blocker, in healthy subjects. Results of single oral administration.:Results of Single Oral Administration
- Pharmacokinetirs of diltiazem in patients with paroxysmal supraventricular tachycardia.
- Various types of caffeine metabolism in Japanese people. Studies by urine per 2 hours.
- Diuretic and uricosuric effects of traxanox sodium in healthy subjects: Comparison with hydrochlorothiazide by multiple-dose study.
- Pharmacokinetic and pharmacological effects of urapidil in healthy volunteers. Comparative study with prazosin.:Comparative Study with Prazosin
- Chronopharmacological study of furosemide in human subjects.
- Pharmacokinetics of beta-methyldigoxin.
- タイトル無し
- タイトル無し
- Pharmacokinetic and pharmacological properties of doxazosin mesilate in Japanese healthy adult volunteers.
- Comparison between direct assay and separating assay of blood beta-methyldigoxin by fluorescent polarized immunoassay.
- タイトル無し
- タイトル無し
- タイトル無し