Synthesis and reactions of 2-arylhydrazinotropones. I. Preparation of 2-(2-arylhydrazino)tropones and the 4-substituted derivatives.
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概要
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A wide variety of 2-(2-arylhydrazino)tropones were prepared by the reactions of 2-tosyloxytropone with arylhydrazines. The dimeric compounds 6,6′-bis(arylhydrazono)-1,1′-bi(2,4-cycloheptadiene)-7,7′-diones, 2-anilinotropones, and 3-(2-arylhydrazino)tropones were isolated as minor products in some cases. Similarly, starting with 2-tosyloxytropones bearing an isopropyl, isopropenyl, (1-acetamidoethyl), and protected acetyl group at the 5-position, 4-substituted 2-(2-arylhydrazino)tropones were obtained as the major products by the abnormal substitution reaction. These 2-(2-arylhydrazino)tropones are expected to effectively serve as precursors for a convenient synthesis of 5-aryl-substituted tropolones via benzidine-type rearrangement. <SUP>1</SUP>H NMR (200 or 500-MHz) parameters for these 4-substituted 2-(2-arylhydrazino)tropones are given for their unambiguous structural assignments.
- 公益社団法人 日本化学会の論文
著者
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Nozoe Tetsuo
Tokyo Research Laboratories Kao Corporation
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Hara Yasushi
Department Of Anatomy And Neurosurgery Shiga University Of Medical Science
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Goto Yasutomo
Department Of Surgery Japanese Red Cross Nagoya First Hospital
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Honda Masaaki
Department Of Computer Engineering Waseda University
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Andoh Takayoshi
Department Of Electrical And Electronic Engineering Faculty Of Engineering Shinshu University
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IMAFUKU Kimiaki
Department of Chemistry, Faculty of Science, Kumamoto University
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Yamamoto Hiroshi
Departmemt Of Chemical Engineering University Of Tokyo
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Yin Bing-Zhu
Department of Chemistry, Faculty of Science, Kumamoto University
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