Substituent effects on the dissociation constants of 1-aryl-5-hydroxy-2-hydroxymethyl-4-pyridones.
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概要
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Six new 1-aryl-5-hydroxy-2-hydroxymethyl-4-pyridones were synthesized and their dissociation constants were measured. Hammett analysis of p<I>K</I><SUB>a</SUB> values for proton gain and proton loss gave the following equations: p<I>K</I><SUB>1</SUB>=2.74–0.34σ and p<I>K</I><SUB>2</SUB>=8.80–0.36σ, respectively.
- 公益社団法人 日本化学会の論文
著者
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IMAFUKU Kimiaki
Department of Chemistry, Faculty of Science, Kumamoto University
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Matsumura Hisashi
Department of Chemistry, Faculty of Science, Kumamoto University
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Takahashi Kumio
Department of Chemistry, Faculty of Science, Kumamoto University
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