STUDIES ON PHARMACODYNAMIC ACTION OF N-ETHYLMALEIMIDE (NEM):3RD REPORT : NEM INDUCED HYPERGLYCEMIA IN RATS
スポンサーリンク
概要
- 論文の詳細を見る
Intraperitoneal injection of NEM to rats, produced marked hyperglycemia, a considerable decrease in liver glycogen and inhibition of glucose uptake in skeletal muscles. It is postulated that these phenomena are due to the acceleration of sugar mobilization from liver glycogen, inhibition of glucose utilization in peripheral organ tissues, and partial mediation of epinephrine released from adrenal medulla. NEM reacted quickly with red cells but not with plasma protein and was inactivated or taken up into red cells, the reason being that when NEM is administered i.v. the action is much weaker.
- 公益社団法人 日本薬理学会の論文
著者
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Masuda Yasusuke
Department Of Toxicology Niigata College Of Pharmacy
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OKADA Nobuyuki
Department of Pharmacology, Wakayama Medical College
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Yamamoto Hiroyuki
Department Of Applied Biology Faculty Of Textile Science And Technology Shinshu University
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MURANO Tadashi
Department of Pharmacology, Wakayama Aledical College
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MASUDA Yasusuke
Department of Pharmacology, Wakayama Aledical College
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YAMAMOTO Hiroyuki
Department of Pharmacology, Wakayama Medical College
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OKADA Nobuyuki
Department of Pharmacology, Wakayama Aledical College
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MURANO TADASHI
Department of Pharmacology, Osaka City University Medical School
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