STUDIES ON THE FUNCTION OF CELL MEMBRANE : 8TH REPORT: BINDING OF CYTOCHROME c TO LIVER PLASMA MEMBRANE AND MICROSOME IN CCl<SUB>4</SUB>-POISONED RATS
スポンサーリンク
概要
- 論文の詳細を見る
Binding ability of liver plasma membranes of normal rats to oxidized form of cytochrome c was more potent than that of microsomes, although this binding was dependent on the buffer concentration of the suspending solution; namely, the higher the concentration of the buffer, the less was the binding of cytochrome c to both fractions. Conversely, the bound cytochrome c was eluted more easily from microsomes than from membranes, the elution pattern also being dependent on the buffer concentration. In the liver of CCl<SUB>4</SUB>-administered rats, the plasma membrane binds the hemoprotein more firmly and releases it less easily than in that of normal ones. Possibility of the elevation of NADH-cytochrome c reductase activity in liver cell membranes after CCl<SUB>4</SUB> administration is discussed.
- 社団法人 日本薬理学会の論文
著者
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Yamamoto Hiroyuki
Department Of Cardiology Kurashiki Central Hospital
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KUCHII Masato
Department of Pharmacology, Wakayama Medical College
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MURANO Tadashi
Department of Pharmacology, Wakayama Medical College
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Masuda Yasusuke
Department Of Toxicology Niigata College Of Pharmacy
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OKADA Nobuyuki
Department of Pharmacology, Wakayama Medical College
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Yamamoto Hiroyuki
Department Of Applied Biology Faculty Of Textile Science And Technology Shinshu University
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MURANO Tadashi
Department of Pharmacology, Wakayama Aledical College
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MASUDA Yasusuke
Department of Pharmacology, Wakayama Aledical College
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YAMAMOTO Hiroyuki
Department of Pharmacology, Wakayama Medical College
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OKADA Nobuyuki
Department of Pharmacology, Wakayama Aledical College
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KUCHII Masato
Department of Pharmacology, Wakayama Aledical College
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MURANO TADASHI
Department of Pharmacology, Osaka City University Medical School
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