経口避妊薬服用中に発見された進行乳癌

概要

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A primary advanced breast carcinoma occurred in a 46-year old woman who had been taking oral contraceptives for twelve years. She was treated by radical mastectomy and bilateral oophrectomy. Histologically, the breast lesion showed scirrhous carcinoma. She became aware of an enlarging nodule in the outer upper quadrant of the right breast six years before admission. The low back pain radiating to the right leg began two months before admission. On admission X-ray film showed metastatic osteolytic figure to the right ilium. After the surgical operation, the pain was relieved and the follow up X-ray film showed improvement of the metastatic lesion of the ilium. She is alive well for two years after the operation.<BR>We suppose that oral cotraceptives made the condition worse in this case. So that, careful observation should be made in the woman taking oral contraceptives.
学校法人昭和大学・昭和医学会の論文