下顎骨転移を来たした胸腺腫の1症例

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A case of thymoma with distant metastasis is reported.The patient, a 46-year-old female, complained of a mass in the left parotid region since January 1979. Prior to the manifestation of the swelling of the parotid region, she was suffering from myasthenia gravis and thymoma, and received an operation for removal of the thymoma in August 1978.At the time of admission to the Department of Otolaryngology, Kumamoto University Hospital, the swelling of the left parotid region was a child first-sized stone like mass and was accompanied by palpebrae ptosis and left facial palsy. Under suspicion of a malignant parotid tumor, an operation was perfomed. However, the tumor originated in the mandibula which was encapsulated and slightly adhered to the surrounding tissues. The tumor was totaly extirpated and histological examination was performed. The microscopic sections showed a metastasis of thymoma composed predominantly of lymphocytes.Bone scintigraphy at two weeks after the operation revealed multiple metastasis. Liver scintigraphy and whole body CT scanning also showed a nodule in the left lobe of the liver which was suspected of being a metastasis.VEMP was administered to treat the patient. Up to present, no recurrence of the symptoms, including those of myasthenia gravis, were noted at the 4-months follow-up.Distant metastasis of thymoma, especially to the mandibula, is extremely rare. A review was made in paticular of the metastatic thymoma.
耳鼻咽喉科臨床学会の論文

下顎骨転移を来たした胸腺腫の1症例

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