Effectiveness of Shin'i-Seihai-To for Sinusitis with Polyp.

概要

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We evaluated the clinical effect of Tsumura Shin'i-Seihai-To (TJ-104), a Kampo medicine, in patients with chronic sinusitis with nasal polyps. The subjects of this study were 45 patients aged 12-81 years, who received Shin'i-Seihai-To 7.5g p. o. per day for 12 weeks. The clinical effectiveness was graded according to 4 parameters. Subjective symptoms, objective signs other than nasal polyps, the size of nasal polyps and X ray signs. The patients' Sho was determined from their answers to an easy questionnaire.The effect of Shin'i-Seihai-To was first examined in all patients before their Sho was known. Then the patients were divided into a Jitsu & Ghukan-Sho group in which Shin'i-Seihai-To was effective and a Kyo-Sho group in which was not effective, and the two groups were compared.It is concluded that Shin'i-Seihai-To had the effect on improvement of subjective symptoms and reduced the size of nasal polyps. Furthermore, the improvement in objective signs was significant in relation to Sho.
耳鼻咽喉科臨床学会の論文