Bifemelane Hydrochloride Therapy for Sudden Deafness.

概要

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Various therapeutic regimens have been used in the treatment of sudden deafness, one of the sensori-neural hearing losses in which recovery is generally considered to be possible in the early stage of the disease. Drugs which improve the blood flow of the inner ear, cerebral metabolism activators and anti-neuritis agents are widely used. We used bifemelane hydrochloride, a cerebral function improver, to treat 80 patients suffering from sudden deafness. The drug was found to be as effective as other medications. Since combination therapies are popular for the treatment of sudden deafness, bifemelane may be a positive drug in combination therapy.Animal experiments were also performed to clarify the mechanism of action of bifemelane. The results indicate that bifemelane dilates cochlear blood vessels and increases blood flow.
耳鼻咽喉科臨床学会の論文