飼料リン量がコイ肝膵臓諸酵素活性に及ぼす影響〔コイの脂質代謝に及ぼす飼料中のリン含量の影響-2-〕

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The activities of several hepatopancreatic enzymes of carp reared at various dietary phosphorus levels were determined. Malnutrition of carp caused by the phosphorus deficiency, which accompanied accumulation of lipid in muscle and viscera, the activity of hepatopancreatic CCE, G/DH and gluconeogenic enzymes (FDPase and PEPCK) appeared to increase, and that of PK decreased remarkably. The activity ratios of both FDPase to PFK and PEPCK to PK increased. This fact shows preponderance of gluconeogenic activity. After fasting for 3 weeks, decrease in the PGDH activity and lipid of the phosphrus deficiency group was much smaller than that of the phosphorus excess group. On the contrary, decrease in PK activity was more significant in the latter. From the results, it is supposed that fatty acids synthesis via citrate from amino acids may be accelerated by the deficeency of phosphorus. In addition, recycling of pyruvate to phosphoenolpyruvate (futile cycle) activated by the dominant PEPCK acitivity, which was much higher than PK activity, would decrease in the activity of the TCA cycle, thus, energy production by the glycolytic pathway, and result in more utilization of amino acids.
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