Nocardia kampachiで免疫したブリの血液中および腹腔内の白血球の動態

概要

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To clarify the immune response of yellowtail Seriola quinqueradiata which was immunized with attenuated live and fbrmalin killed Nocardia kampachi, changes in composition of peripheral and peritoneal leucocytes of yellowtail were examined after intra-peritoneal insertion of a capsule filled with the bacteria. Serum agglutination antibody titer increased(〉1, 000)in groups immunized with either attenuated live bacteria or formalin killed bacteria. However, changes in number and composition of peripheral and peritoneal leucocytes in fish immunized with attenuated live bacteria differed significantly from changes observed in fish immunized with formalin killed bacteria and from controls. In the group immunized with attenuated live bacteria, the number of lymphocytes, monocytes and granulocytes increased in peripheral blood;peritoneal lymphocytes, macrophages and granulocytes quickly accumulated in the capsules and the bacteria were phagocytosed within 72h. It was found that the reaction of peripheral leucocytes and the accumulation of peritoneal leucocytes around the bacteria was more rapid in the group immunized with live bacteria than in the group immunized with formalin killed bacteria.
日本水産學會の論文