上顎に発生した悪性線維性組織球腫の1例-電顕ならびに免疫組織化学的検索-

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A malignant fibrous histiocytoma (MFH) arising from the left maxilla of a 55-year-old woman is reported. According to Weiss and Enzinger, this tumor was a pleomorphic-striform type of MFH. At present, it seems to be difficult to make a differential diagnosis, although the diagnostic criteria for MFH have been proposed. To make further investigation, electronmicroscopy, histochemistry and immuno-histochemistry were utilized. The ultrastructure revealed the presence of histiocyte-like cells as composing cells. The positive immuno-histochemical reactions with anti-α1 lysozyme, anti-arantitrypsin, anti-α1-antichymotrypsin antibodies suggested histiocytic character of tumor cells. It is emphasized that these immuno-histochemical and electron microscopic studies are available for differential diagnosis of this tumor.
社団法人日本口腔外科学会の論文