悪性リンパ腫 (ML) の臨床病理学的および免疫学的解析 : 10症例の検討 (1976-1985)

概要

論文の詳細を見る
Ten cases of malignant lymphoma examined clinically, histopathologically and immunophenotypically are reported. 1) This study comprised of 8 males and 2 females patients; the majority advanced in age. Half were nodal lymphomas and half were extranodal. 2) According to Ann Arbor staging classification, 3 cases were seen in each of Stages I, II and U. One case was excluded because it was a relapse. Histologically, all were non-Hodgkin's lymphomas comprising of small lymphocytic (1), mixed small and large cell (1), diffuse large cell (2), large cell, immunoblastic (4) and small non-cleaved cell (2), according to the Working Formulation. Six were of high grade malignancy. 3) The immunophenotypic analysis for surface markers examined in 8 cases revealed that seven had characters of B-cells and only one had those of T-cells. 4) Cases of Stage I or II were usually treated with irradiation in the past. But chemotherapy combined with radiotherapy has recently been put into practice even for most cases in these Stages. 5) Only one patient is now surviving. The results clearly show that the prognosis of malignant lymphoma, especially in high grade, is extremely poor.
社団法人日本口腔外科学会の論文