口腔外科領域の各種感染症に対するセフブペラゾン (CBPZ, ケイペラゾン) の臨床成績

概要

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Clinical evaluation of cefbuperazon (CBPZ, Keiperazon) in various infections in the field of oral surgery were carried out. Cefbuperazon was administered by intravenous injection at a daily dose of 2g (1g×2 times) to 60 patients with various infections. The following results were obtained: Cases consisted of 39 with maxillary ostitis, 7 phlegmon of the floor of the mouth, 5 buccal abscess, 4 odontgenic maxillary sinuitis, 3 post operative maxillary cyst, 1 peritonsillitis and 1 sialoadenitis submandibularis. The evaluation was made with 59 cases. The clinical effects obtained in subjective judgement were excellent in 26 cases, good in 26 cases, fair in 5 and poor in 2. The clinical effects obtained in judgement by point were classified as excellent in 16 cases, good in 36 and poor in 7. Effective rate in subjective was 88.2%. Effective rate in judgement by point was 88.2%. As side effects, eruption and itching appeared in one case, diarrhea in two and nausea in one. The elevation of s-GOT and s-GPT was observed after cefbuperazon administration in 4 cases in the laboratory examiations. The results indicated the usefulness of cefbuperazon in the treatment of various infections in the field of oral surgery.