口腔外科領域の各種感染症に対するセフタジジム (CAZ, モダシン®) の臨床的検討

概要

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Clinical study of Ceftazidime (CAZ, Modacin, ®) in various infections in the field of oral surgery were carried out. Ceftazidime was administered by intravenous injection at a daily dose of 2g (1g 2 times) to 49 patients with various infections. Cases consisted of 31 with ostitis of the jaws, 5 phlegmon of the floor of the mouth, 3 periocoronitis, 2 odontogenic maxillary sinusitis, 1 postoperative maxillary cyst, 2 peritonsillar abcess, 2 buccal abcess, 1 temporal abcess, 1 lymphadenitis and 1 sialoadenitis submandibularis. The following results were obtained. The clinical effects obtained in subjective judgement were excellent in 21 cases, good in 24 cases, fair in 2 and poor in O. The clinical effects obtained in judgement by point were classified as excellent in 13 cases, good in 32 and poor in 2, the effective rate of which was 95.7%, the same as the former. As for side effects, skin eruption, hypotention, nausea, and stomatic discomfort appeared. In the laboratory examinations, elevation of s-GOT in one case was observed. The results indicated the usefullness of Ceftazidime in the treatment of various infections in the field of oral surgery.