Nd-YAGレーザーの及ぼす口腔軟組織への影響 (1) : 頬粘膜創の病理組織学的, 生化学的検索

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Recently, in the field of oral surgery, use of the Nd-YAG laser has obtained excellent results for the medical treatment of several diseases. However, postirradiative affects, such as swelling, pain, ulceration, masticatory disturbance, etc., can occur. Macroscopic, histopathological and biochemical investigations following laser irradiation were undertaken in experiments on animals. In the healing of the stress caused by laser irradiation, it was recognized that the duration of the healing period depended not only on the output but also the duration of irradiation. Early in the investigations of laser treatment, the difference in healing was also recognized as being affected by the focus distance of laser irradiation. In addition, biochemically, hydroxyproline levels fell immediately after irradiation, and at 4 days post treatment, reached the lowest level. After that time, rising levels were observed. The change of the III/ I ratio was recognized to rise and reach a peak at 7 days.