92歳女性の頬粘膜に初発した脂腺癌の1例

概要

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Sebaceous carcinoma is a rare tumor originating from sebaceous glands, Meibomian glands and Zeis glands. On the other hand, ectopia of sebaceous glands is a well-known phenomenon in the head and neck, particularly in such locations as the mucocutaneous junction, the buccal mucosa and the salivary glands. A few cases of sebaceous carcinoma in the parotid glands were reported. But there were no reports of carcinomas arising from the sebaceous components in oral and paraoral sites. Generally, wide local excision has been the most common treatment. Radiotherapy efficacy has not been adequately assessed. In the paper, we present a case with sebaceous carcinoma which was thought to occur from Fordyce's condition or minor salivary gland in the buccal mucosa. A patient a 92-year-old woman, had sebaceous carcinoma of the left buccal mucosa and the left cheek and lung metastasis. We performed local excision and radiotherapy in this case. The effect of radiotherapy was satisfactory and the tumor of the cheek disappeared after irradiation. But, the patient died of advancement of metastasis without local recurrence 5 monthes after radiation.