口腔外科領域における緻密質顆粒水酸化アパタイト骨補填材の臨床評価-9施設における共同研究-

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Several authors reported differences in the tissue response, biocompatibility, stability and osteoconduction of hydroxyapatite (HAP) granules depending on their chemical composition, type (porous or non-porous), shape, solubility behaviour, conditions of production or implant site. Bonetite is one type of non-porous, unabsorbable hydroxyapatite (HAP) granules. We used Bonetite to fill bone defects caused by extraction of erupted teeth (erupted tooth group, 75 cases) or impacted teeth (impacted tooth group, 14 cases) and removal of jaw cysts, apical granulomas or benign tumors (cyst group, 49 cases), and evaluated the usefulness of this material in nine clinics. The following results were obtained: 1) Inflammation of the implant site was comparable to general wound healing after the operation. 2) No side effects were noted. 3) Secondary surgical treatment was done in 4 cases (2.9%), who showed good progress. 4) The incidence of wound dehiscence was 9.9%, leakage of HAP granules 27.5% and infection 2. 9% within 1 month after operation. However, the incidence of these findings decreased 3 months after operation, and they were not noted 6 months after operation. 5) The mean final retention rate of HAP granules was 84.5% in the erupted tooth group, 92.5% in the impacted tooth group, 90.0% in the cyst group and 86.7% overall. 6) As a result, Bonetite was evaluated to be markedly useful or moderately useful in 119 cases (86.2%). 7) In conclusion, Bonetite was considered to be one of the most useful implant materials to fill bone defects in the oral and maxillofacial region.
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口腔外科領域における緻密質顆粒水酸化アパタイト骨補填材の臨床評価-9施設における共同研究-

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