抗菌性を有する界面活性剤についての研究 (第5報) : 界面活性を有する染料の合成と抗菌性

概要

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Malachite Green derivatives bearing butyl, hexyl, octyl and decyl group were prepared by the condensation reaction of <I>N, N</I>-dimethylaniline with alkylbenzaldehydes which had been obtained from alkylbenzenes by chloromethylation followed by oxidation. Surface tension of aqueous solutions of these derivatives were determined by electro surface balance and it was found that the surface tension lowered with an increase of the carbon number of the alkyl group and surface tension of aqueous solution of the decyl derivative was about 27 dyn /cm. <BR>Antimicrobial and antifungal activities were evaluated in terms of minimum inhibitory concentration by a dilution method. Their activities increased markedly with decrease in the number of carbon in the alkyl group. The butyl derivative showed the highest activity among these derivatives, and the activity was comparable to that of a commercial cationic surfactant. <BR>Dyeing properties of these derivatives for some bacterial cells and textiles were also examined.
社団法人日本油化学会の論文