Bacterial Aerosol に関する研究 : 第7報空中ブドウ球菌および人の身体の常在ブドウ球菌が産生する DNase 活性

概要

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A quantitative analysis of the deoxyribonuclease (DNase) activity in airborne staphylococci dispersed by healthy volunteers and in resident staphylococci collected from them compared the production of coagulase. The results were as follows:1. DNase activities in airborne coagulase-positive staphylococci (CPS) were almost the same as in a standard Staphylococcus aureus strain (FDA 209 P). In 84% of airborne coagulase-negative staphylococci (CNS), DNase activities were observed accounting, however, for less than 10% of those in CPS.2. DNase activities in airborne CNS decreased markedly after 30min incubation at 100°C. This suggests that DNase in airborne CNS is different from the heat resistant DNase in Staphylococcus aureus.3. The level of DNase activity in resident CNS was remarkably lower than in resident CPS. In 13 CNS strains isolated from the nose and skin, however, the values were similar to those of CPS. DNase in these staphylococci were heat-resistant. Thus, they may be mutants of Staphylococcus aureus which have lost the ability to produce coagulase.