Biological and Immunological Characterization of Human Luteinizing Hormone Discharged by the Stimulation of Synthetic Luteinizing Hormone-Releasing Hormone (LH-RH) in Normal and Anovulatory Women
スポンサーリンク
概要
- 論文の詳細を見る
Plasma samples were obtained by repeated venopunctures immediately before, and at 15, 30, 60, 120 and 180 min after intravenous bolus administration of 100μg synthetic LH-RH in normal and various anovulatory women. Plasma hLH levels were determind by an <I>in vitro</I> bioassay and a radioimmunoassay with improved reagents. The LH-RH stimulation induced an abrupt elevation of both biological and immunological hLH activities in normal and anovulatory women, although the responsiveness to LH-RH differed from case to case. Both elevated biological and immunological hLH activities decreased gradually with a half disappearance time of 122.4±27.9 min and 112.5±25.4 min, respectively (Mean±S. D.). A transient and significant depression in the ratio of biological to immunological hLH activities (B/I ratio) was observed at 15 min after the LH-RH administration in normal subjects. This depression is attributable to the cross-contamination of an increased amount of hLH subunits induced by LH-RH stimulation. The B/I ratios were significantly elevated throughout the investigation period in the anovulatory patients when compared with those in the normal subjects. This elevation appears to indicate the increased discharge of special type (s) of hLH subpopulations of high biological potency in the anovulatory cases.
- 社団法人 日本内分泌学会の論文
著者
-
Koizumi Yukio
Department Of Biochemistry Akita University School Of Medicine
-
Nakajima Akira
Department Of Applied Electronics Tokyo Institute Of Technology
-
Suginami Hiroshi
Department Of Obstetrics And Gynecology Clinical Research Unit Kyoto National Hospital
-
HAMADA Katsuyuki
Department of Obstetrics and Gynecology Ehime University School of Medicine
-
YANO MARIKO
Department of Obstetrics and Gynecology, School of Medicine, Ehime University
-
MASAOKA HISASHI
Department of Obstetrics and Gynecology School of Medicine, Ehime University
-
Yano Mariko
Department Of Gastroenterology Ehime Prefectural Central Hospital
-
YANO MARIKO
Department of Obstetrics and Gynecology School of Medicine, Ehime University
-
Koizumi Yukio
Department of Applied Biological Science, Tokyo University of Agriculture and Technology
-
KOIZUMI YUKIO
Department of Obstetrics and Gynecology School of Medicine, Ehime University
関連論文
- A Proposal of a Novel RFID Tag with Biomedical Signal Sensing Functions
- REG I enhances chemo- and radiosensitivity in squamous cell esophageal cancer cells
- CLINICAL FEATURES OF JAPANESE LEBER'S HEREDITARY OPTIC NEUROPATHY WITH 11778 MUTATION OF MITOCHONDRIAL DNA
- Droplet Size Dependence of Line Tension for an Ionic Liquid on a Smooth Silane Coating
- INTERCALATION BEHAVIOR OF VARIOUS FATTY ACIDS INTO Mg-Al-LAYERED DOUBLE HYDROXIDE
- Preparation of Pt particles dispersing nanocomposites by thermal treatment of tetrachloroplatinate/layered double hydroxide (LDH)
- Effect of Liquid Viscosity on the Internal Fluidity of a Droplet Sliding on a Fluoroalkylsilane Coating
- Voltage swing interval effects on photocatalytic decomposition of 1, 4-dioxane in aqueous media using TiO_2-coated stainless mesh( Innovative Ceramic Materials and Technologies for Global Environmental Protection)
- Slipping and Rolling Ratio of Sliding Acceleration for a Water Droplet Sliding on Fluoroalkylsilane Coatings of Different Roughness
- Effect of Electrification Conditions on the Freezing of Supercooled Water Droplets on a Hydrophobic Coating
- Effects of Vacuum Ultraviolet Light Illumination on the Residual Stress in Sol-Gel-derived Titanium Dioxide Films
- Effect of Roughness on Lipophobicity of a Surface Prepared Using Boehmite Nanoparticles and Fluoroalkylsilane
- Sliding Mode Transition of Water Droplet on the Silicon Surface Coated with Octadecyltrichlorosilane
- Transplantation of rat hepatic stem-like (HSL) cells with collagen matrices
- Simaomicin α, a polycyclic xanthone, induces G_1 arrest with suppression of retinoblastoma protein phosphorylation
- Laparoscopic Surgery for Endometriosis : A Long Term Follow-Up
- Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice
- Phytotoxicity of Indole-3-acetic Acid Produced by the Fungus, Pythium aphanidermatum
- A Novel Diol-derivative of Chalcone Produced by Bioconversion, 3-(2,3-Dihydroxyphenyl)-1-phenylpropan-1-one, Activates Phosphorylation of ERK and CREB in Cultured Rat Cortical Neurons
- High-Level Fluoroquinolone Resistance in Pseudomonas aeruginosa Due to Interplay of the MexAB-OprM Efflux Pump and the DNA Gyrase Mutation
- Development of Three-dimensional FE Modeling System from the Limited Cone Beam CT Images for Orthodontic Tipping Tooth Movement
- Uptake of Uranium from Sea Water by Microalgae : Studies on the Accumulation of Heavy Metal Elements in Biological Systems (VI)
- S9-6 Effects of tumor necrosis factor-α and glial cell lined-neurotrophic factor on the toxicity-induced by methamphetamine in vivo and in vitro(SYMPOSIUM 9: MOLECULAR MECHANISMS OF DRUG DEPENDENCE)(Proceedings of the 31st Annual Meeting)
- Bestatin, an Aminopeptidase Inhibitor, Promotes Follicular Growth and Ovulation Suppressed by Stress in Mice
- High Density Two-Dimensional Hole Gas Induced by Negative Polarization at GaN/AlGaN Heterointerface
- Freezing Behavior of a Water Droplet on a Rough Hydrophobic Surface Coated with a Short-chained Fluoroalkylsilane
- Negative Line Tension for an Ionic Liquid on a Hydrophobic Fluoroalkylsilane Coating
- Allelic Loss of Chromosome 16q in Endometrial Cancer : Correlation with Poor Prognosis of Patients and Less Differentiated Histology
- Honeybee Royal Jelly Stimulates CRE-mediated Transcription in a PKA- but Not MEK/ERK-dependent Manner in PC12D Cells
- 1/f Fluctuations in the Dielectric Response of Triglycine Sulfate : Thermal and Statistical Properties
- Genetic Approaches to the Molecular/Neuronal Mechanisms Underlying Learning and Memory in the Mouse
- Effect of Mechanical Deformation on Permeation of Hydrogen in Iron
- Association of Replication Error Positive Phenotype with Lymphocyte Infiltration in Endometrial Cancers
- Effect of Sulbactam on Anti-Pseudomonal Activity of β-Lactam Antibiotics in Cells Producing Various Levels of the MexAB-OprM Efflux Pump and β-Lactamase
- Effect of Acetic Acid and Vinegar on Blood Glucose and Insulin Responses to Orally Administered Sucrose and Starch(Food & Nutrition)
- Biomechanical influences on the upper vertebrae during mastication, an examination using the finite element method
- Mechanism of Gold Adsorption by Persimmon Tannin Gel
- Adsorption of Uranium by Vegetable Crude Drugs(Biological Chemistry)
- A Case of Laparoscopic Complication : Injury of the Left Common Iliac Vessels and Subsequent Acute Compartment Syndrome of the Left Leg
- Biological and Immunological Characterization of Human Luteinizing Hormone Discharged in a Pulsatile Fashion in the Normal Menstrual Cycle
- Biological and Immunological Characterization of Human Luteinizing Hormone Discharged by the Stimulation of Synthetic Luteinizing Hormone-Releasing Hormone (LH-RH) in Normal and Anovulatory Women
- A Trial for the Improvement of the in vitro Bioassay for Human Luteinizing Hormone
- Measurements of Human Luteinizing Hormone in Plasma by in vitro Bioassay and by Conventional and Improved Radioimmunoassays
- Preparative Studies of ZnO Varistors I. : Effect of Calcination on the V-I Characteristics of ZnO Varistors
- HDI-26 THE EVAPORATION AND READSORPTION OF LUBRICANT FILM MOLECULES IN HARD DISKS
- A convenient controlling apparatus simply realized with inexpensiveelectronic parts and its application to the temperature dependences of electroceramicmaterials
- Qualitative and Quantitative Changes in Plasma Luteinizing Hormone (LH) under Stimulation by Intravenous Infusion of Synthetic Luteinizing Hormone-Releasing Hormone (LHRH) in Japanese Monkeys (Macaca fuscata) as Assessed by Electrofo-cusing
- Control of static and dynamic hydrophobicity of solid surface and its application
- Possible Applications of Electrophysiology in Ophthalmic Clinics(SYMPOSIUM ON ELECTRORETINOGRAPHY)
- A Preliminary Study of Some Ion-conductive Mixtures
- Shear Stress Analysis of EHL Oil Films Based on Thermal EHL Theory - Effect of Inlet Oil Temperature -
- Wetting Mode Transition of Water Droplets by Electrowetting on Highly Hydrophobic Surfaces Coated with Two Different Silanes
- SF6-Based Deep Reactive Ion Etching of (001) Rutile TiO2 Substrate for Photonic Crystal Structure with Wide Complete Photonic Band Gap
- Meta-analysis of genome-wide association scans for genetic susceptibility to endometriosis in Japanese population
- Fibrinolytic Activation Promoted by the Cyclopentapeptide Malformin: Involvement of Cytoskeletal Reorganization
- Growth of Low-Dislocation-Density AlN under Ga Irradiation
- Studies on Luminescence Characteristics of Fine Semiconductor Particles in Glasses and Ceramics I. : Effect of Oxidation on the Luminescent Properties of Small Semiconductor Grains in Silicic Media
- Bronchial Schwannoma Masquerading as Cause of Hemoptysis in a Patient with Pulmonary Embolism
- Pott's Disease and Cold Abscesses
- Anti-Melanogenesis Effect of Glechoma hederacea L. Extract on B16-Murine Melanoma Cells
- Accumulation of Uranium by Chlorella Cells Grown under Autotrophic, Heterotrophic and Mixotrophic Culture Conditions
- Influences of Long-term Tolbutamide Administration on Diabetic Syndrome in Alloxan Rabbits
- Sliding Tribological Behaviors of Cu and Fe against Si3N4 under Electrolysis
- Preparative Studies of ZnO Varistors II. : Additive Effects of Some Metallic Oxides on the V-I Characteristics of ZnO Varistor Devices
- Dipolar Interaction in TEMPAD Biradical
- Studies of Ceramic Gas Sensors : Effects of Various Oxide Additives
- Pott's Disease and Cold Abscesses
- Study of Zinc Oxide Varistors with Relation to the Mode of Preparation andAddition of Transition Metal Oxides
- Magnetic Properties of Some Iminoxyl Polyradicals. II. TEMPOP Triradical and TEMPOS Tetraradical
- CD47 regulates the TGF-.BETA. signaling pathway in osteoblasts and is distributed in Meckel's cartilage
- Characterization of Glycosylphosphatidylinositol-Anchored Ceruloplasmin Enriched in the Apical Plasma Membrane of Rat Hepatocytes
- Syntheses and crystal structures of diaquatris(m-hydroxybenzoato)lanthanoid(III) m-hydroxybenzoic acid dihydrate (M=La,Ce,Pr, and Nd), and di-.MU.-(m-hydroxybenzoato)bis{triaquabis(m-hydroxybenzoato)lanthanoid(III)}dihydrate (M=Sm,Gd,Dy,Er, and Yb).