Multiagent chemotherapy for children with advanced neuroblastoma. A comparison of high-dose cyclophosphamide, vincristine and adriamycin therapy with James' therapy plus adriamycin.:A Comparison of High-Dose Cyclophosphamide, vincristine and Adriamycin Th

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概要

• 論文の詳細を見る

• Sixteen children with Stage III and N neuroblastoma were treated using two different chemotherapy protocols; six with a James' therapy plus adriamycin, and ten with a regimen consisting of high-dose cyclophosphamide, vincristine and adriamycin in a nonrandomized fashion. The highdose cyclophosphamide with vincristine and adriamycin appeared to improve the duration of survival; that is, in the patients treated by this protocol, the median survival duration was 25 months, the one-year survival rate was 75% and the three-year survival rate was 50%. On the other hand, none of the patients treated by James' therapy plus adriamycin survived for more than one year. Their median survival was only four months.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• Noguchi Akihiko

  Department of Pediatric Surgery, Kurume University School of Medicine

• Yano Hiromichi

  Department Of Pediatric Surgery Kurume University School Of Medicine

• Tanaka Tetsuro

  Department Of Biopharmaceutics School Of Pharmacy Fukuyama University

• YANO HIROMICHI

  Departments of Pediatric Surgery Kurume University School of Medicine

• HIYOSHI YASUHIKO

  Departments of Pediatrics Kurume University School of Medicine

• HORIKOSHI TAMAKI

  Departments of Pediatrics Kurume University School of Medicine

• IRIE YASUSHI

  Departments of Pathology Kurume University School of Medicine

• HIYOSHI YASUHIKO

  Department of Pediatrics and Child Health, Kurume University School of Medicine

• HORIKOSHI TAMAKI

  Department of Pediatrics, Kurume University School of Medicine

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