Experimental study on the development of liver cell carcinoma. Role of histamine in chronic liver injury.:ROLE OF HISTAMINE IN CHRONIC LIVER INJURY
スポンサーリンク
概要
- 論文の詳細を見る
Role of autotallergic mechanism on the chronicity of liver diseases with special reference to histamine, which is said to be one of the chemical media tors and plays a large part in antigen antibody reaction, was investigated experimentally.Under the administration of homologous liver antigen with histamine to rabbits, liver injury closely resembling chronic active hepatitis could be de veloped, which progressed into liver cirrhosis with pseudolobulus formation. This result may indicate that the progression of chronic hepatitis into liver cirrhosis can be regarded as one process. Estrogen promotes antigen anti body reaction and plays a large part in prolongation and aggregation of liver diseases. Furthermore, liver cell carcinoma was demonstrated in one animal and epithelial hyperplasia of bile ductules in two animals. This fact may sug gest that chronic hepatitis changes into malignant tumor and perpetual anti genic stimulation has a large role in the development and progression of malignant tumor and role of histamine should never be ignored.
- The Keio Journal of Medicineの論文
著者
-
Suzuki Osamu
Department Of Cardiology Iwate Prefectural Iwai Hospital
-
Ishii Kohdoh
Department Of Internal Medicine National Minami Yokohama Hospital
-
Kiryu Yasuyoshi
Department Of Medicine Keio University
-
Tsuchiya Masaharu
Department Of Internal Medicine Keio University
-
ISHII KOHDOH
Department of Internal Medicine, School of Medicine, Keio University
-
KIRYU YASUYOSHI
Department of Internal Medicine and Surgery, School of Medicine, Keio University
-
KIRYU YASUYOSHI
Department of Internal Medicine, School of Medicine, Keio University
関連論文
- A case of erythropoietic protoporphyria with liver cirrhosis suggesting a therapeutic value of supplementation with α-tocopherol
- Highly Sensitive Electrochmiluminescence Immunoassay Using the Ruthenium Chelate-Labeled Antibody Bound on the Magnetic Micro Beads
- High-dose-rate Brachytherapy Combined with Long-term Hormonal Therapy for High-risk Prostate Cancer : Results of a Retrospective Analysis
- Intracavitary Brachytherapy for Carcinoma of the Uterine Cervix : Comparison of HDR (Ir-192) and MDR (Cs-137)
- Purification and Characterization of a Novel Fungal α-Glucosidase from Mortierella alliacea with High Starch-hydrolytic Activity(Biochemistry & Molecular Biology)
- -1008-NON-INVASIVE EVALUATION OF DECELERATION OF THE LEFT VENTRICULAR FLOW VELOCITY DURING AUXOTONIC CONTRACTION : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -P83-MECHANISM OF AUSTIN FLINT MURMUR IN MID-DIASTOLE AND IN PRE-SYSTOLE : Echocardiography, Pulsed Doppler : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -217-ECHOCARDIOGRAPHIC EVALUATION OF THE MODE IN PROGRESSION OF EXERCISE INDUCED MYOCARDIAL ISCHEMIA : Ischemic Heart Disease I : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -551- PREDICTION OF CORONARY ARTERY LESIONS AND SEVERITY BY EXERCISE TWO-DIMENSIONAL ECHOCARDIOGRAPHY
- -161- A NEW METHOD FOR ESTIMATING SEVERITY OF AORTIC STENOSIS USING PULSED DOPPLER ECHOCARDIOGRAPHY : Myocardial Infarction, Valvular Heart Disease : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SO
- SERIAL CHANGES IN REGIONAL LEFT VENTRICULAR WALL MOTION DURING ERGOMETER EXERCISE IN PATIENTS WITH ISCHEMIC HEART DISEASE : COMPARATIVE STUDY WITH ECG CHANGES (2nd REPORT) : Exercise Test (II) : FREE COMMUNICATIONS (VI) : PROCEEDINGS OF THE 49th ANNUAL SC
- EXERCISE TWO-DIMENSIONAL ECHOCARDIOGRAPHY : COMPARATIVE STUDY OF WALL MOTION AND ECG DURING ERGOMETER EXERCISE : Excercise Test : IV : 48 Annual Scientific Meeting, Japanese Circulation Society
- A STUDY OF BLOOD FLOW VELOCITY PATTERN IN ATRIAL SYSTOLE BY PULSED DOPPLER ECHOCARDIOGRAPHY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Echocardiography (I)
- SERIAL CHANGES IN LEFT VENTRICULAR WALL MOTION SUBSEQUENT TO ACUTE MYOCARDIAL INFARCTION AND THEIR PROGNOSTIC SIGNIFICANCE : A 2-D ECHO STUDY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Ischemic Heart Disease
- ANALYSIS OF HEMODYNAMICS IN PULMONARY HYPERTENSION BY PULSED DOPPLER ECHOCARDIOGRAPHY : Electrophysiology : 46th Annual Scientific Meeting, Japanese Circulation Society
- Cloning, Characterization, and Expression of cDNA Encoding a Lipase from Kurtzmanomyces sp. I-11(Biochemistry & Molecular Biology)
- Purification and Characterization of a Lipase from the Glycolipid-Producing Yeast Kurtzmanomyces sp. I-11(Biochemistry & Molecular Biology)
- Isolation of Yeast Kurtzmanomyces sp. I-11, Novel Producer of Mannosylerythritol Lipid(Microbiology & Fermentation Technology)
- Efficacy of Long-term Flecainide Therapy in Patients with Paroxysmal Atrial Fibrillation : Analysis Based on Time of Onset
- Novel correction methods as alternatives for the six-dimensional correction in CyberKnife treatment
- Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry
- -299-COMPARATIVE STUDY OF SERIAL CHANGES OF REGIONAL WALL MOTION, ECG AND ANGINAL PAIN : EXERCISE TWO-DIMENSIONAL ECHOCARDIOGRAPHY : Excercise Test : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION S
- Lipid Composition of a Newly Isolated Polyunsaturated Fatty Acid-Producing Fungus, Achlya sp.ma-2801
- Neurological manifestations of knockout mice with β-galactosidase deficiency
- Sensitive Analysis of Blonanserin, a Novel Antipsychotic Agent, in Human Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
- Toward Elucidating the Full Spectrum of Mite Allergens : State of the Art
- Simultaneous determination of selegiline and desmethylselegiline in human body fluids by headspace solid-phase microextraction and gas chromatography-mass spectrometry
- Differentiation and Monitoring of Cells Using a Biochip for Regenerative Medicine : Differentiation of Bone Marrow Stromal Cells and Myoblasts
- -335- ASSESSMENT OF HYPERTENSIVE HEART BY 2-D ECHO IN GROUP MEDICAL EXAMINATION
- DIAGNOSIS OF MYOCARDIAL Ischemia BY SERIAL ST/T CHANGES DURING RECOVERY PHASE OF EXERCISE STRESS TEST : Exercise Testing Ischemia : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Simultaneous determination of barbiturates in human biological fluids by direct immersion solid-phase microextraction and gas chromatography-mass spectrometry
- An autopsy case of human skeletal remains with a numerical variation in thoraco-lumbar vertebrae
- A case of death due to rescue action by power shovel after being buried alive
- Sensitive determination of four general anaesthetics in human whole blood by capillary gas chromatography with cryogenic oven trapping
- Sensitive determination of pethidine in body fluids by surface ionization organic mass spectrometry
- A curious autopsy case of accidental carbon monoxide poisoning in a motor vehicle
- Analyses of butyrophenones and their analogues in whole blood by high-performance liquid chromatography-electrospray tandem mass spectrometry
- Use of an ion-pairing reagent for high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry determination of anionic anticoagulant rodenticides in body fluids
- Ultra-sensitive method for determination of ethanol in whole blood by headspace capillary gas chromatography with cryogenic oven trapping
- Headspace solid-phase microextraction and gas chromatographic determination of dinitroaniline herbicides in human blood, urine and environmental water
- An ultrastructural study of the liver in erythropoietic protoporphyria
- Extracellular Secretion of Free Fatty Acids by Disruption of a Fatty Acyl-CoA Synthetase Gene in Saccharomyces cerevisiae
- Grouping Newly Isolated Docosahexaenoic Acid-Producing Thraustochytrids Based on Their Polyunsaturated Fatty Acid Profiles and Comparative Analysis of 18S rRNA Genes
- Evidence of Isozymes for Δ6 Fatty Acid Desaturase in Rat Hepatocytes(Biochemistry & Molecular Biology)
- Enzymatic Preparation of Glycerides Rich in Docosahexaenoic Acid from Thraustochytrid Single Cell Oils by Candida rugosa Lipase
- Identification and Expression of a Rat Fatty Acid Elongase Involved in the Biosynthesis of C18 Fatty Acids(Biochemistry & Molecular Biology)
- Lack of Effect of the Abnormal Fatty Acid Metabolism in NC/Nga Mice on Their Atopic Dermatitis
- Purification and Characterization of Sea Squirt α-N-Acetylgalactosaminidase
- STUDY OF ISOVOLUMIC CONTRACTION PHASE BLOOD FLOW PATTERN (a) IN LEFT VENTRICULAR OUTFLOW WITH DOPPLER ECHOCARDIOGRAPHY : Electrophysiology : 46th Annual Scientific Meeting, Japanese Circulation Society
- 70. Bilateral Carotid Artery Occlusion with Germinal Center in the Thymus : A case Report
- Production and Properties of Phytase and Acid Phosphatase from a Sake Koji Mold,Aspergillus oryzae
- Transgene Insertion Pattern Analysis Using Genomic Walking in a Transgenic Mouse Line
- Chromosomal Mapping and Zygosity Check of Transgenes Based on Flanking Genome Sequences Determined by Genomic Walking
- Ovarian Localization of Immunoglobulin G and Inhibin α-Subunit in Guinea Pigs after Passive Immunization against the Inhibin α-Subunit
- Production of Polyunsaturated Fatty Acids by Genetic Engineering of Yeast
- Contribution of Translin to Hematopoietic Regeneration after Sublethal Ionizing Irradiation(Highlighted paper selected by Editor-in-chief,Molecular and Cell Biology)
- Effect of Genetic Background on Establishment of Mouse Embryonic Stem Cells
- MgB_2超伝導線材における臨界電流の向上
- PJ-653 The Relationship between Long-term Preventive Effect of Antiarrhythmic Drug Therapy and Symptomatic Thromboembolism in Patients with Lone Paroxysmal Atrial Fibrillation(Cerebrovascular circulation/Stroke-3 (H) PJ110,Poster Session (Japanese),The 70
- PJ-312 Different Efficacy of Combination Therapy with Antiarrhythmic Drugs and Enalapril between the Patients Groups with and without Underlying Heart Disease(Arrhythmia, therapy-14 (A) PJ53,Poster Session (Japanese),The 70th Anniversary Annual Scientific
- PE-021 The Combination Therapy with Antiarrhythmic Drugs and Pravastatin in Patients with Lone Atrial Fibrillation Prevents the Development of Structural Remodeling(Arrhythmia, diagnosis/pathophysiology/EPS-6 (A) PE4,Poster Session (English),The 70th Anni
- OJ-118 Long-term Prognosis of Antithrombotic Therapy According to Guideline Recommended by Japanese Circulation Society in Patients with non-valvular Paroxysmal Atrial Fibrillation(Thromboembolism/Antithrombotic therapy/Thrombolysis-2 (H) OJ20,Oral Presen
- Angiotensin Converting Enzyme Inhibitor Enhances Efficacy of Amiodarone and not Class-I Antiarrhythmic Drug in Preventing Recurrence of Paroxysmal Atrial Fibrillation(Arrhythmia, Pharmacological Therapy 2 (A), The 69th Annual Scientific Meeting of the Jap
- Relationship between the Response to Antiarrhythmic Drug Therapy and the Development of Structural Remodeling in Patients with Paroxysmal Atrial Fibrillation(Arrhythmia, Diagnosis/Pathophysiology/EPS 3 (A), The 69th Annual Scientific Meeting of the Japane
- Pravastatin Enhances the Efficacy of Class I Antiarrhythmic Agents in Patients with Paroxysmal Atrial Fibrillation and Hyperlipidemia(Arrhythmia, Non-pharmacological Therapy 8 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Efficacy of Antiarrhythmic Therapy in Preventing Recurrence of Paroxysmal Atrial Fibrillation not Showing Any Circadian Variation in the Onset(Arrhythmia, Pharmacological Therapy 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
- Long-Term Prognosis of Patients With Paroxysmal Atrial Fibrillation Depends on Their Response to Antiarrhythmic Therapy
- PJ-197 Characteristics of patients with paroxysmal atrial fibrillation and diabetes mellitus and long-term preventive efficacy of antiarrhythmic agents(Arrhythmia, Pharmacological Therapy 2 (A) : PJ33)(Poster Session (Japanese))
- PE-111 A randomized crossover study on the long-term efficacy of pilsicainide and cibenzoline in preventing recurrence of paroxysmal atrial fibrillation(Arrhythmia, Pharmacological Therapy 1 (A) : PE19)(Poster Session (English))
- PE-108 The long-term preventive effect of amiodarone in patients with paroxysmal and persistent atrial fibrillation; Analysis based on patients characteristics(Arrhythmia, Pharmacological Therapy 1 (A) : PE19)(Poster Session (English))
- OJ-375 The relationship between the long-term preventive effect of antiarrhythmic agents and symptomatic thromboembolism in patients with paroxysmal atrial fibrillation(Thromboembolism/Thrombolysis 3 (IHD) : OJ45)(Oral Presentation (Japanese))
- OE-336 The relationship between the duration of arrhythmia and subsequent preventive effect of amiodarone in patients with paroxysmal/persistent atrial fibrillation(Arrhythmia, Pharmacological Therapy 4 (A): OE42)(Oral Presentation (English))
- The Long-Term Efficacy of Amiodarone in Patients with Paroxysmal Atrial Fibrillation : Comparison of Groups between with and without Heart Failure
- Angiotensin Converting Enzyme Inhibitor Enhances the Efficacy of Antiarrhythmic Agents in Patients with Paroxysmal Atrial Fibrillation and Essential Hypertension
- Tumor Cell Proliferation of Hepatocellular Carcinoma, with Special Reference to Ultrasonographic Findings and Arterial Vascularity by US Angiography
- Preimplantation Embryo Development in Mastomys (Praomys coucha) In Vivo and In Vitro
- The Relationship between Sperm Morphology and In Vitro Fertilization Ability in Mice
- The restriction of all minerals in the diet enhancing paraquat toxicity is regarded primarily as the shortage of Mg
- Determination of iodide in urine using electrospray ionization tandem mass spectrometry
- Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid
- Development of Embryos in Superovulated Guinea Pigs following Active Immunization against the Inhibin α-Subunit
- Diamine Oxidase Activities in Catfish Tissues : Physiology
- IDENTIFICATION AND QUANTITATION OF 5-HYDROXYTRYPTAMINE IN THE RETINAE OF COW, PIG AND CHICK BY GAS CHROMATOGRAPHY/MASS SPECTROMETRY
- Establishment and characterization of new human Burkitt's lymphoma cell lines (HBL-7 and HBL-8) that are highly metastatic in SCID mice : A metastatic SCID mouse model of human lymphoma lines
- Multinucleated giant cells recruited by implantation of octacalcium phosphate (OCP) in rat bone marrow share ultrastructural characteristics with osteoclasts
- Simple Isotope Dilution Headspace-GC-MS Analysis of Naphthalene and p-Dichlorobenzene in Whole Blood and Urine
- Separation methods for amino group-possessing pesticides in biological samples
- Influence of feeding regime on timing of parturition in beef cattle and the relationship of vaginal temperature to parturition
- A New Class of Domains of Holomorphy $(\mathbf{II})$ (Domains of holomorphy on a three dimensional Stein space with an isolated singularity)
- A Gauge Theory for the Kadomtsev-Petviashvili System
- A New Class of Domains of Holomorphy (III) (Reinhardt domains of holomorphy on a 3-dimensional analytic set with a ($\textbf{C}^\ast )^2$-action)
- Sudden Death with Massive Hemoptysis from Rupture of a Thoracic Inflammatory Aortic Aneurysm: An Autopsy Case Report
- Supplement to "Pseudoconvex Domains on a Kahler Manifold with Positive Holomorphic Bisectional Curvature"
- STUDIES ON THE MICROCIRCULATION UNDER THE INFLUENCE OF THE AUTONOMIC NERVE IRRITATION
- Experimental study on the development of liver cell carcinoma. Role of histamine in chronic liver injury.:ROLE OF HISTAMINE IN CHRONIC LIVER INJURY
- Effects of reduced glutathione on experimental hemorrhagic shock.
- FOLLOW-UP STUDY OF SERUM IMMUNOGLOBULINS IN THYMECTOMIZED CASES OF MYASTHENIA GRAVIS
- MYXOID LEIOMYOSARCOMA OF THE UTERUS
- Highly stereoselective palladium(0)-catalyzed allylation of active methylene compounds with allyl imidates under neutral conditions.
- Recent progress and new perspectives in lymphoma glycobiology