一側性内耳障害(メニエール病など)の治療 : 硫酸ストレプトマイシン中耳腔注入の遠隔成績

概要

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Injection of streptomycin sulfate into the middle ear cavity was performed for treatment of frequent attacks of vertigo casused by unilateral inner ear le-sions such as Ménières Disease (57 cases), unilateral inner ear hypofunction with unilaterally reduced caloric responses (10 cases), severe benign paroxysmal positional vertigo (BPPV) (5 cases). These 72 cases of inner ear lesions had frequent attacks of vertigo and they refused surgical therapy.<BR>After the injection of streptomycin sulfate into the middle ear cavity, the vertiginous attacks disappeared, however they needed constant trainings to regain equilibrium. These subjects were observed for 6 months to 13 years after the injection. After this treatment, their tinnitus was the same or less than before the injection. The hearing remained the same as the pre-injection in cases of unilateral inner ear hypofunction, or BPPV. However, in 2 cases of Ménières Disease, the hearing of the lesion side was strongly impaired soon after the injection. In the other cases of Ménières Disease, the hearing was the same as before the injection or improved. In 2 cases of Ménières Disease, the contralateral hearing of low tone was reduced.