平衡障害の日常生活動作による評価--塩酸ビフェメラン(セレポ-ト)の効果

概要

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The usefulness of bifemelane hydrochloride was evaluated in 99 patients with dysequilibrium. The severity of both subjective and objective vestibular findings were studied before and after the administration of bifemelane hydrochloride 150 mg/day for more than 4 weeks. Equilibrium grading by self-assessment was based on the handicap inventory of dysequilibrium composed of 11 daily activities. The degree of effectiveness evaluated by subjective and objective findings was 85.9%. Side effects were observed in 3 out of 121 patients (2.5%), but none were serious. Significant improvement of the handicap inventory of dysequilibrium scores was demonstrated after treatment with bifemelane hydrochloride.