Clinical features of 26 cases with anti-thyroid hormone autoantibodies.

概要

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We have experienced 26 cases with anti-thyroid hormone autoantibodies. Clinical features, evaluation of the results of thyroid function tests and whether or not the thyroid hormone resistance is present in these patients were evaluated. Thyroid hormone values measured by a double antibody RIA, a solid phase RIA, or an analog method RIA showed apparently high values, whereas those measured by a single antibody RIA showed apparent low values compared with the clinical manifestations, respectively. It was concluded that measurement of serum FT3 and FT4 after 12.5% PEG treatment as well as the measurement of serum TSH values is useful in the evaluation of real thyroid function in patients with anti-thyroid hormone antibodies.From the supplemental dose of T4 or T3 to maintain hypothyroid patients due to Hashimoto's thyroiditis in euthyroidism, it was concluded that there is no thyroid hormone resistance in such patients.
日本臨床免疫学会の論文