Basic Fibroblast Growth Factor and Epidermal Growth Factor Promote Survival of Primary Cultured Cerebellar Neurons from Neonatal Rats.
スポンサーリンク
概要
- 論文の詳細を見る
Neurotrophic effects of CS23, a mutein of human basic fibroblast growth factor (bFGF), and recombinant human epidermal growth factor (hEGF) were compared in dissociated cerebellar cultures from embryonic (E20) and early postnatal (P0-5) rats. Both CS23 and hEGF promoted the survival of cerebellar neurons without distinction of ages of animals used. The maximum effects of CS23 were always larger than those of hEGF. These results suggest that both bFGF and EGF also function as neurotrophic factors in postnatal cerebellum.
- 公益社団法人 日本薬理学会の論文
著者
-
Abe Kazuho
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
-
Saito Hiroshi
Department of Applied Chemistry, Graduate School of Engineering, Tohoku University
-
Takayanagi Megumi
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
関連論文
- 5歳以下発症日本人1型糖尿病発症に関する免疫学的特徴に関する検討
- The Secular Trend in the Incidence of Subarachnoid Hemorrhage in Miyagi, Japan : 1979-1990
- Relationship between the Required Coefficient of Friction and Gait Initiation in Young Adults on a Low Friction Floor
- Frequencies of factors of metabolic syndrome at diagnosis in children with T2DM
- Modulation of Voltage-Gated Ca^ Current by 4-Hydroxynonenal in Dentate Granule Cells(Highlighted paper setected by Editor-in-cfiief)(Pharmacology)
- Protective effect of S-allyl-L-cysteine, a garlic compound, on amyloid β-protein-induced cell death in nerve growth factor-differentiated PC12 cells
- Morphine augments excitatory synaptic transmission in the dentate gyrus through GABAergic disinhibition
- Defect in an Intrahepatic Degradation of Apolipoprotein B in Suncus: An Animal Model of Hypobetalipoproteinemia^1
- Role of Acyl Coenzyme A Cholesterol Acytransferase in Intrahepatic Processing of apo B-Lipoprotein in Suncus
- Defect in Assembly Process of Very-Low-Density Lipoprotein in Suncus Liver: An Animal Model of Fatty Liver
- Minimally Invasive Direct Coronary Artery Bypass Grafting for Third-Time Coronary Artery Revascularization
- SECRETORY MECHANISM AND PATHOPHYSIOLOGICAL ROLE OF HUMAN ATRIAL NATRIURETIC PEPTIDE IN MEN : Atrial Natriuretic Polypeptide (II) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- SPECIALITY OF ATRIAL FIBRILLATION IN WPW SYNDROME : Arrhythmias (II), Electrophysiology (II), Mapping : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- Tuberous sclerosis, associated with renal cell carcinoma and angiomyolipoma, in a patient who developed endstage renal failure after nephrectomy
- Role of cytokines in anaphylactoid reaction with marked eosinophilia in a hemodialysis patient
- A female patient with malarial nephropathy
- CLINICAL STUDY ON THE SURGICAL TREATMENT OF SEPTAL ACCESSORY PATHWAY IN THE WPW SYNDROME : Arrhythmias (II) : FREE COMMUNICATIONS (III) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Effects of fadrozole and leuprorelin acetate on aromatase activity and cell proliferation in a human breast cancer cell line (SK-BR-3)
- Inhibitory Effects of Catecholamines and Maternal Stress on Aromatase Activity in the Fetal Rat Brain
- Video-Assisted Blebectomy Using a Flexible Scope and a Bleb Implement
- The intensity of scattered light in turbid seawater is a major factor in the turbiditaxis of Japanese anchovy larvae
- Hepatocellular Carcinoma with a Sarcomatous Appearance : Report of a Case
- Direct Calculation of Source Parasitic Resistance in AlGaAs/GaAs HEMTs
- Pleural Involvement of Dialysis-Related Amyloidosis
- The PPARγ Ligand, 15d-PGJ_2, Attenuates the Severity of Cerulein-Induced Acute Pancreatitis
- Pulmonary pleomorphic carcinoma producing hCG
- Poorly Differentiated Adenocarcinoma with Signet-Ring Cell Carcinoma in a Hyperplastic Polyp of the Stomach : Report of a Case
- Fabry disease in patients receiving maintenance dialysis
- Pharmacological Activities of Glycyrrhetinic Acid Derivatives : Analgesic and Anti-Type IV Allergic Effects(Medeicinal Chemistry,Chemical)
- -P121-ENDOTHELIN INHIBITS RENIN RELEASE FROM ISOLATED RAT GLOMERULI : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- The Influence of Inflammatory Cytokines on Estrogen Production and Cell Proliferation in Human Breast Cancer Cells
- A Japanese Family with Ferroportin Disease Caused by a Novel Mutation of SLC40A1 Gene: Hyperferritinemia Associated with a Relatively Low Transferrin Saturation of Iron
- New Analytical Method for Pancreas and Liver Regeneration : Normalization of Streptozotocin-Induced Hyperglycemia by Retrograde Injection of Insulin Producing Cells
- FACTORS AFFECTING ON SODIUM METABOLISM IN SHR (S). A SERIAL OBSERVATION FROM 4 TO 20 WEEKS OF AGE : Hypertension(II) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- -0281-ELECTROPHYSIOLOGIC AND HEMODYNAMIC STUDY FOR ATRIAL FIBRILLATION IN WOLFF-PARKINSON-WHITE SYNDROME
- Secondary Hyperparathyroidism in Patients on Maintenance Hemodialysis : Study of Optimal Hemopurification and Parathyroidectomy
- TNF-α augments the expression of RhoA in the rat bronchus
- Growth Interruption Effect on the Formation of CdSe/ZnSe Quantum Dots
- Generation and Evaluation of Post-Heated Zinc and Selenium Molecular Beams
- A Case of Malignant Pheochromocytoma with Holt-Oram Syndrome
- Improvement of Fatigue and Acceleration of Recovery from Stress-Induced Deficient Sexual Behavior in Mice Following Oral Administration of Soft-Shelled Turtle Powder
- Anti-tumor Effects of Orally Administered Soft-Shelled Turtle Powder in Mice
- Human T-Lymphotropic Virus Type-I Infection, Antibody Titers and Cause-specific Mortality among Atomic-bomb Survivors
- PTHrP and PTH/PTHrP Receptor Expressions in Human Endometrium
- The Role of Parathyroid Hormone-Related Protein in Intra-Tracheal Fluid
- The Effect of Cytokines on Parathyroid Hormone-Related Protein (PTH-rP) Production in Human Amnion Cells
- Molecular Beam Epitaxially Grown ZnSe(001) Surface Studied by the In Situ Observation of RHEED Intensity
- Effect of Residual Strain on the Splitting of Excitonic Luminescence Lines in Epitaxially Grown ZnSe/GaAs
- Antagonistic Effect of N - (3 - Aminopropyl)cyclohexylamine on Neurotrophic Action of Spermine in Primary Cultured Rat Hippocampal and Cerebellar Neurons
- The Effects of Ethanol and Crocin on the Induction of Long-Term Potentiation in the CA1 Region of Rat Hippocampal Slices
- Structural Requirement for Neurotrophic Activity of Spermine in Cultured Rat Hippocampal Neurons
- Cushing's Syndrome due to Bilateral Adrenocortical Adenomas with Unique Histological Features
- Na^+ and K^+ Dependence of L-Glutamate-Induced Suppression of Astrocyte Stellation in Culture
- Activin Selectively Abolishes Hippocampal Long-Term Potentiation Induced by Weak Tetanic Stimulation In Vivo
- Antiemetic Effects of Morphine on Motion- and Drug-Induced Emesis in Suncus murinus
- Furosemide : Sensitive Calcium Rise Induced by GABA_A : Receptor Stimulation in Cultures of Embryonic Rat Striatal Neurons
- Involvement of a Peripheral Mechanism in the Emesis Induced by Cardiac Glycosides in Suncus murinus
- Body Mass Index Negatively Influences Glycated Albumin, but not Glycated Hemoglobin, in Diabetic Patients
- AC Flashover Characteristics on Trapezoidal Contamination Models of Actual Insulators
- IS-54 Production of Macrophage Migration Inhibitory Factor(MIF)from Granulosa Cells at Ovulatory Phase
- Effects of Pitavastatin on Serum Lipids and High Sensitivity C-Reactive Protein in Type 2 Diabetic Patients
- Marine Molluscs Collected from the Shallow Waters of Hainan Island, South China Sea, by China-Japan Joint Research in 1997
- K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma
- Malignant transformation of endometriosis : application of laser microdissection for analysis of genetic alterations according to pathological changes
- Intramolecular Carbostannylation of Allyl- and Vinylstannanes via a Radical Chain Process
- Hydroxy Group-Directed Homolytic Hydrostannylation of Alkenols with Dibutylchlorostannane
- Recent advances in non-invasive prenatal DNA diagnosis through analysis of maternal blood
- Flow Velocity Measurement in Rotating Cavities by using Particle Image Velocimetry
- Heat Transfer and Pressure Drop Characteristics of a Heat Exchanger with Vortex Generators
- CP2289,a New 5-HT_3 Receptor Ligand : Agonistic Activities on Gastroenteric Motility
- 3β-Hydroxysteroid Dehydrogenase Activity in Human Osteoblast-Like Cells
- A Study of γ-Aminobutyric Acid (GABA) in Amniotic Fluid
- Low Temperature Growth of ZnSe/GaAs Using Post-Heated Molecular Beams
- β_1-Adrenergic receptor mediation in the lichen glucan PB-2-induced enhancement of long-term potentiation in the rat dentate gyrus in vivo
- Optimum Culture Conditions for Production of Exfoliative Toxin by Staphylococcus hyicus
- High-frequency stimulation of the basolateral amygdala facilitates the induction of long-term potentiation in the dentate gyrus in vivo
- Roles of GABA^A, NMDA and muscarinic receptors in induction of long-term potentiation in the medial and lateral amygdala in vitro
- Effect of Hexacyanoferrate(III) on Mycobacterium smegmatis 7Fe Ferredoxin: Further Evidence for Formation of a 6Fe(2×[3Fe-4S]) Ferredoxin
- Diffuse neuroaxonal leukodystrophy with spheroids of adult onset: MRI and pathological studies
- Influence of the Hand Breaking at Sideways Falls : Sharing Effective Mass and Impact Force (Proceedings of the 54th Meeting of Japan Society of Physiological Anthropology)
- Evaluation of L-Glutamate Clearance Capacity of Cultured Rat Cortical Astrocytes
- Differential Effects of Microtubule Inhibitors on Axonal Branching and Elongation of Cultured Rat Hippocampal Neurons
- Amyloid β Peptide Specifically Promotes Phosphorylation and Nuclear Translocation of the Extracellular Signal-Regulated Kinase in Cultured Rat Cortical Astrocytes
- The Induction of Long-Term Potentiation at Amygdalo-Hippocampal Synapses in Vivo(Pharmacology)
- L-Glutamate Suppresses Astrocyte Stellation Induced by Actin Breakdown in Culture
- Histamine H_3 Receptor-Mediated Inhibition of Excitatory Synaptic Transmission in the Rat Dentate Gyrus In Vivo
- Cimetidine Inhibits the Induction of Long-Term Potentiation in the Dentate Gyrus of Rats In Vivo
- The Anticonvulsive Effect of Glutathione in Mice
- Developmental Changes in Cyclic AMP-Stimulated Stellation of Cultured Rat Cortical Astrocytes
- Amyloid β protein enhances the clearance of extracellular _L-glutamate by cultured rat cortical astrocytes
- Amyloid β protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes
- The p44/42 mitogen-activated protein kinase cascade is involved in the induction and maintenance of astrocyte stellation mediated by protein kinase C
- Modulation of Hippocampal Long-Term Potentiation by the Amygdala: A Synaptic Mechanism Linking Emotion and Memory
- Menadione Toxicity in Cultured Rat Cortical Astrocytes
- Cholesterol dose not affect the toxicity of amyloid β fragment but mimics its effect on MTT formazan exocytosis in cultured rat hippocampal neurons
- Deficiency of .BETA.-adrenoceptor-mediated relaxation in Suncus trachea.
- Basic Fibroblast Growth Factor and Epidermal Growth Factor Promote Survival of Primary Cultured Cerebellar Neurons from Neonatal Rats.
- Involvement of Protein Kinase Activation in Neurotrophic Effects of Basic Fibroblast Growth Factor in Cultured Brain Neurons.
- A comparison of neurotrophic effects of epidermal growth factor and basic fibroblast growth factor in primary cultured neurons from various regions of fetal rat brain.
- Pharmacological Isolation and Characterization of NMDA Receptor-Mediated Synaptic Potential in the Dentate Gyrus of Rat Hippocampal Slices.