CP2289,a New 5-HT_3 Receptor Ligand : Agonistic Activities on Gastroenteric Motility

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概要

• 論文の詳細を見る

• A new 5-HT_3 receptor ligand, CP2289,was synthesized and pharmacologically tested. Although CP2289 inhibited the Bezold-Jarisch reflex, it contracted the excised ileal muscle of mice, rats and guinea pigs. This response may reflect a partial agonist character of CP2289 in the gut. In vivo antiemetic and gastric emptying tests gave similar results.

• 公益社団法人日本薬学会の論文
• 1997-07-15

著者

• SAITO HIROSHI

  Department of Neurology, Tohoku University School of Medicine

• MATSUKI Norio

  Department of Chemical Pharmacology,Faculty of Pharmaceutical Sciences

• Matsuki Norio

  Lab. Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences The Univ. Of Tokyo Jpn

• Matsuki N

  Univ. Tokyo Tokyo Jpn

• Izumi Masaaki

  Pharmaceutical Research Center Meiji Seika Kaisha

• Kurata Y

  Pharmaceutical Research Center Meiji Seika Kaisha

• HACHISU MITSUGU

  Pharmacology and Toxicology laboratories and Pharmaceutical Research Laboratories, Meiji Seika Kaish

• 斉藤 博満

  協和発酵・東京研

• Imai M

  Mitsubishi Chemical Corp. Ibaraki Jpn

• SATO Yasuo

  Pharmaceutical Research Center, Meiji Seika Kaisha

• KONNO Fukio

  Pharmaceutical Research Center, Meiji Seika Kaisha

• Kurata Yasushi

  Pharmaceutical Research Center Meiji Seika Kaisha

• Matsuki Norio

  Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences

• Matsuki Norio

  Graduate School Of Pharmaceutical Sciences The University Of Tokyo

• Matsuki Norio

  Department Of Chemical Pharmacology Faculty Of Pharmaceutical Science The University Of Tokyo

• Konno Fukio

  Pharmaceutical Research Center Meiji Seika Kaisha

• Imai Megumi

  Pharmaceutical Research Center Meiji Seika Kaisha

• AMANO Kazuko

  Pharmaceutical Research Center, Meiji Seika Kaisha

• IWAMATSU Katsuyoshi

  Pharmaceutical Research Center, Meiji Seika Kaisha

• SAKAKIBARA Shiro

  Pharmaceutical Research Center, Meiji Seika Kaisha

• Amano K

  Shizuoka Children's Hospital Shizuoka Jpn

• Sakakibara Shiro

  Pharmaceutical Research Center Meiji Seika Kaisha

• Iwamatsu Katsuyoshi

  Pharmaceutical Research Center Meiji Seika Kaisha

• Saito H

  Department Of Pharmacology College Of Pharmacy Nihon University

• Hachisu Mitsugu

  Pharmaceutical Research Center Meiji Seika Kaisha

• Saito Hiroshi

  Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine

• Matsuki Norio

  Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences The University Of Tok

• Sato Yasuo

  Pharmaceutical Research Center Meiji Seika Kaisha

• Hachisu Mitsugu

  Pharmaceutial Research Center, Meiji Kaisha, LTD.

• Saito Hiroshi

  Department of Applied Chemistry, Graduate School of Engineering, Tohoku University

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