Familial Aggregation of Uterine Myomas in Japanese Women.
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概要
- 論文の詳細を見る
To assess the familial aggregation of uterine myomas in Japanese women with myomas, one hundred forty four women requiring surgery for myomas and 288 age-matched healthy controls were studied in Hokkaido, Japan. The incidence of positive first-degree family history of myomas among women aged 45-54 years with myomas was greater than that among controls (31.5% versus 15.2%, respectively, p < 0.01). Analyses categorized by the status of parity and familiality among subjects showed that the risk for myomas was the greatest in women who had both fewer births (parity = 0 or 1 ) and the positive family history of myomas as compared with those who had both more births (parity 2) and the negative familiality of myomas (odds ratio = 5.8, 05% confidence interval = 2.3 --14 8). The results of this study suggest that Japanese middle-aged women with myomas have the familial predisposition of uterine myomas. Furthermore, nulliparous women with the familial aggregation of myomas may be at increased risk of the disease. J Epidemiol, 2002 ; 12 : 240-253
- 日本疫学会の論文
著者
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Mori Mitsuru
Department Of Community Health Science Saga Medical School
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Miyake Hirotsugu
Department Of Environmental And Public Health Sapporo Medical College
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Kudo Ryuichi
Department Of Gynecology And Obstetrics Sapporo Medical University School Of Medicine
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Sato Fumio
Department Of Astronomy And Earth Sciences Tokyo Gakugei University
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Nishi Motol
Department of Public Health, School of Medicine, Sapporo Medical University
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